Results 21 to 30 of about 3,331,551 (411)

Ligand-independent androgen receptors promote ovarian teratocarcinoma cell growth by stimulating self-renewal of cancer stem/progenitor cells

open access: yesStem Cell Research, 2014
Background: Ovarian teratocarcinoma (OVTC) arises from germ cells and contains a high percentage of cancer stem/progenitor cells (CSPCs), which promote cancer development through their ability to self-renew.
Wei-Min Chung   +6 more
doaj   +1 more source

Long non-coding RNAs potentially function synergistically in the cellular reprogramming of SCNT embryos

open access: yesBMC Genomics, 2018
Background Long non-coding RNAs (lncRNAs), a type of epigenetic regulator, are thought to play important roles in embryonic development in mice, and several developmental defects are associated with epigenetic modification disorders.
Fengrui Wu   +9 more
doaj   +1 more source

On the role of dauer in the adaptation of nematodes to a parasitic lifestyle

open access: yesParasites & Vectors, 2021
Nematodes are presumably the most abundant Metazoa on Earth, and can even be found in some of the most hostile environments of our planet. Various types of hypobiosis evolved to adapt their life cycles to such harsh environmental conditions.
Lieke E. Vlaar   +7 more
doaj   +1 more source

Bisphenol A interferes with lncRNA Fhadlos2 and RUNX3 association in adolescent mouse ovary

open access: yesEcotoxicology and Environmental Safety, 2023
Bisphenol A (BPA) has a number of adverse effects on the reproductive development of females. In particular, the mechanism of disruption of ovarian development in adolescent mice is still unclear.
Yilei Zhang   +9 more
doaj   +1 more source

Hormone replacement therapy [PDF]

open access: yes, 2012
Martha Hickey, Jane Elliott, Sonia Louise ...
Davison, S., Elliott, C., Hickey, M.
core   +2 more sources

Luteinizing hormone-releasing hormone antagonists [PDF]

open access: yesExpert Opinion on Therapeutic Patents, 2009
Luteinizing hormone-releasing hormone (LH-RH) plays a central role in the vertebrate reproduction by regulating gonadal activity. Based on its binding to pituitary LH-RH receptors, as well as to LH-RH receptors expressed on cancer cells, LH-RH agonists and antagonists have been developed for different therapeutic applications.Here we give an overview ...
Mezö, Gábor, Manea, Marilena
openaire   +3 more sources

Omics for understanding the tolerant mechanism of Trichoderma asperellum TJ01 to organophosphorus pesticide dichlorvos

open access: yesBMC Genomics, 2018
Backgroud Though it is toxic to humans, dichlorvos is a widely used chemical pesticide and plays an important role in the control of plant pests. The application of a combination of the biocontrol agent Trichoderma with dichlorvos may reduce the need for
Qiong Wu   +5 more
doaj   +1 more source

The role of strigolactones in P deficiency induced transcriptional changes in tomato roots

open access: yesBMC Plant Biology, 2021
Background Phosphorus (P) is an essential macronutrient for plant growth and development. Upon P shortage, plant responds with massive reprogramming of transcription, the Phosphate Starvation Response (PSR). In parallel, the production of strigolactones (
Yanting Wang   +7 more
doaj   +1 more source

Modern possibilities of phytotherapy for male infertility from the standpoint of evidence-based medicine

open access: yesResearch Results in Pharmacology, 2023
Introduction: Male infertility is an topical medical and social problem of modern reproductive medicine. Its pharmacotherapy is often empirical in nature, and the most popular method remains the use of various herbal substances (phytotherapy), the ...
Oleg I. Bratchikov   +2 more
doaj   +1 more source

Multiple levels of crosstalk in hormone networks regulating plant defense

open access: yesThe Plant Journal, 2020
Summary Plant hormones are essential for regulating the interactions between plants and their complex biotic and abiotic environments. Each hormone initiates a specific molecular pathway and these different hormone pathways are integrated in a complex ...
N. Aerts   +2 more
semanticscholar   +1 more source

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