Results 31 to 40 of about 2,113,176 (343)

Postrecruitment Function of Yeast Med6 Protein during the Transcriptional Activation by Mediator Complex

open access: yesBiochemistry Research International, 2018
Med6 protein (Med6p) is a hallmark component of evolutionarily conserved Mediator complexes, and the genuine role of Med6p in Mediator functions remains elusive.
Gwang Sik Kim, Young Chul Lee
doaj   +1 more source

Gentiana lutea attenuates hepatotoxicity induced by ketoconazole in rats by fortifying the cellular antioxidant defense system

open access: yesJournal of Basic and Applied Zoology, 2023
Background Ketoconazole (KET) is a broad-spectrum antifungal drug that has been reported to induce hepatotoxicity in humans and animals. Methods The safe guarding response of Gentiana extract (GEN) against KET-induced hepatotoxicity was investigated in ...
Alaaeldin Ahmed Hamza   +4 more
doaj   +1 more source

Genome-Wide Identification, Functional Analysis and Expression Profiling of the Aux/IAA Gene Family in Tomato [PDF]

open access: yes, 2012
Auxin is a central hormone that exerts pleiotropic effects on plant growth including the development of roots, shoots, flowers and fruit. The perception and signaling of the plant hormone auxin rely on the cooperative action of several components,among
Abel   +55 more
core   +3 more sources

Stressless sampling to improve diagnostics of catecholamine excess: new assay to determine metanephrines in saliva

open access: yesEndocrine Connections
Determination of metanephrines in saliva has been reported as a pain- and hazard-free alternative to plasma-based tests with a potential to reduce false-positive results during diagnostic work-up for neuroendocrine tumours.
Per M Thorsby   +4 more
doaj   +1 more source

Circadian and Ultradian Rhythms of Free Glucocorticoid Hormone Are Highly Synchronized between the Blood, the Subcutaneous Tissue, and the Brain [PDF]

open access: yes, 2012
Total glucocorticoid hormone levels in plasma of various species, including humans, follow a circadian rhythm that is made up from an underlying series of hormone pulses. In blood most of the glucocorticoid is bound to corticosteroid-binding globulin and
Droste, Susanne K   +4 more
core   +1 more source

Growth Hormone-Releasing Hormone in Diabetes [PDF]

open access: yesFrontiers in Endocrinology, 2016
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland. In addition, GHRH is an important regulator of cellular functions in many cells and organs.
Louis H. Philipson   +4 more
openaire   +4 more sources

Hawthorn Herbal Preparation from Crataegus oxyacantha Attenuates In Vivo Carbon Tetrachloride -Induced Hepatic Fibrosis via Modulating Oxidative Stress and Inflammation

open access: yesAntioxidants, 2020
Hawthorn (HAW) is a herbal preparation extracted from Crataegus oxyacantha. HAW has cardioprotective, antioxidants, anti-inflammatory, and anti-hypotensive effects. HAW’s effect on hepatic fibrosis remains, however, unknown.
Alaaeldin Ahmed Hamza   +5 more
doaj   +1 more source

Hormones, damned hormones, and statistics [PDF]

open access: yesBJOG: An International Journal of Obstetrics & Gynaecology, 2017
Deputy Editor‐in‐Chief, Dr Michael Marsh, discusses his top articles from this issue in an audio podcast available at: https://soundcloud.com/bjog/september-editors-choice-2017.
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

External radiotherapy of thyroid cancer [PDF]

open access: yes, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
core   +1 more source

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