Results 61 to 70 of about 3,277,448 (363)

Anti‐androgen enzalutamide enhances prostate cancer neuroendocrine (NE) differentiation via altering the infiltrated mast cells → androgen receptor (AR) → miRNA32 signals

Molecular Oncology, 2015
The recently developed anti‐androgen enzalutamide also known as (MDV3100) has the advantage to prolong by 4.8 months the survival of castration resistant prostate cancer (CRPC) patients. However, the mechanisms behind the potential side effects involving
Qiang Dang, Lei Li, Hongjun Xie, Dalin He, Jiaqi Chen, Wenbing Song, Luke S. Chang, Hong-Chiang Chang, Shuyuan Yeh, Chawnshang Chang   +9 more
doaj   +1 more source

Second to fourth digit ratio (2D:4D) and concentrations of circulating sex hormones in adulthood [PDF]

, 2011
BACKGROUND: The second to fourth digit ratio (2D:4D) is used as a marker of prenatal sex hormone exposure. The objective of this study was to examine whether circulating concentrations of sex hormones and SHBG measured in adulthood was associated with 2D:
Bassett, J, English, DR, Giles, GG, Hopper, JL, Manning, JT, Morris, HA, Muller, DC, Severi, G   +7 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Exploring the Genetic Link Between Thyroid Dysfunction and Common Psychiatric Disorders: A Specific Hormonal or a General Autoimmune Comorbidity [PDF]

, 2022
Sourena Soheili‐Nezhad, Emma Sprooten, Indira Tendolkar, Marco Medici   +3 more
openalex   +1 more source

Comparing plasma and faecal measures of steroid hormones in Adelie penguins Pygoscelis adeliae [PDF]

, 2010
Physiological measurements of both stress and sex hormones are often used to estimate the consequences of natural or human-induced change in ecological studies of various animals.
Banks, Jonathan C., Bell, Dudley G., Bright, A., Carey, P.W., Chandler, J., Hudson, Q.J., Ingram, J.R., Ling, Nicholas, Lyall, K., Morgan, Dai K.J., Möstl, E., Nakagawa, Shinichi, Ninnes, Calum Edward, Stevens, Mark I., Waas, Joseph R., Wallace, J.   +15 more
core   +2 more sources

Diagnosis, Genetics, and Therapy of Short Stature in Children: A Growth Hormone Research Society International Perspective

Hormone Research in Paediatrics, 2019
The Growth Hormone Research Society (GRS) convened a Workshop in March 2019 to evaluate the diagnosis and therapy of short stature in children. Forty-six international experts participated at the invitation of GRS including clinicians, basic scientists ...
P. Collett-Solberg, G. Ambler, P. Backeljauw, M. Bidlingmaier, B. Biller, M. Boguszewski, P. Cheung, Catherine S. Choong, L. Cohen, P. Cohen, A. Dauber, C. Deal, C. Gong, Y. Hasegawa, A. Hoffman, P. Hofman, R. Horikawa, A. Jorge, A. Juul, P. Kamenickỷ, V. Khadilkar, J. Kopchick, B. Kriström, M. Lopes, Xiaoping Luo, B. Miller, M. Misra, I. Netchine, S. Radovick, M. Ranke, A. Rogol, R. Rosenfeld, P. Saenger, J. Wit, J. Woelfle   +34 more
semanticscholar   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Biotransformation of zearalenone to non-estrogenic compounds with two novel recombinant lactonases from Gliocladium

BMC Microbiology
Background The mycotoxin zearalenone (ZEA) produced by toxigenic fungi is widely present in cereals and its downstream products. The danger of ZEA linked to various human health issues has attracted increasing attention.
Zongping Sun, Yuting Fang, Yaohuan Zhu, Wen Tian, Junjie Yu, Jun Tang   +5 more
doaj   +1 more source

The effects of brood stock size on the economy of catfish (Clarias anguillaris) fry production using the hormone induced natural breeding technique [PDF]

, 2005
89 ripe female brooders of the catfish, Clarias anguillaris (Body wt. Range 150g-1, 200g) were induced to spawn by hormone (Ovaprim) induced natural spawning technique over a period of 10 weeks.
Madu, C.T., Offor, C.
core   +1 more source

External radiotherapy of thyroid cancer [PDF]

, 2001
Differentiated thyroid cancer comprises papillary, mixed papillary-follicular and follicular adenocarcinomas. They are mostly hormone-sensitive and respond to thyroid-stimulating hormone (TSH) suppression. The standard treatment is total thyroidectomy. I-
Dühmke, Eckhart, Pollinger, B.
core   +1 more source