Protective Activities of Growth Hormone-Releasing Hormone Antagonists against Toxin-Induced Endothelial Injury [PDF]
GHRH regulates the secretion of GH from the anterior pituitary gland, previously associated with cancer progression and inflammation. An emerging body of evidence suggests that GHRHAnt support endothelial barrier function, but the mechanisms mediating ...
Saikat Fakir, Nektarios Barabutis
doaj +2 more sources
Gonadotropin-Releasing Hormone Antagonists-A New Hope in Endometriosis Treatment? [PDF]
Rzewuska AM +7 more
europepmc +3 more sources
Efficacy and safety of oral gonadotropin-releasing hormone antagonists in moderate-to-severe endometriosis-associated pain: a systematic review and network meta-analysis. [PDF]
Xin L, Ma Y, Ye M, Chen L, Liu F, Hou Q.
europepmc +3 more sources
Oral Gonadotropin-Releasing Hormone Antagonists in the Treatment of Endometriosis: Advances in Research. [PDF]
Wang JY, Zhang Y, Ding J.
europepmc +3 more sources
Draft Genome Sequence of Streptomyces silvensis ATCC 53525, a Producer of Novel Hormone Antagonists. [PDF]
Johnston CW, Li Y, Magarvey NA.
europepmc +3 more sources
Both inflammation and anti-inflammation are involved in the protection of retinal cells. Antagonists of the hypothalamic growth hormone-releasing hormone receptor (GHRHR) have been shown to possess potent anti-inflammatory properties in experimental ...
Ling-Ping Cen +3 more
doaj +1 more source
Differential Changes in Expression of Stress- and Metabolic-related Neuropeptides in the Rat Hypothalamus during Morphine Dependence and Withdrawal [PDF]
Chronic morphine treatment and naloxone precipitated morphine withdrawal activates stress-related brain circuit and results in significant changes in food intake, body weight gain and energy metabolism.
Ferenczi, Szilamér +6 more
core +13 more sources
Androgen deprivation therapy and side effects: are GnRH antagonists safer?
Androgen deprivation therapy (ADT) with gonadotropin-releasing hormone (GnRH) agonists and antagonists is the mainstay of advanced prostate cancer treatment. Both drug classes decrease levels of luteinizing hormone and follicle-stimulating hormones (FSH),
Stephen J Freedland +1 more
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Impact of Androgen Deprivation Therapy on Cardiovascular Outcomes in Prostate Cancer
PurposeSubstantial evidence indicates that men with prostate cancer are at an increased risk for cardiovascular disease, and medical and surgical androgen deprivation therapy is associated with further increased cardiovascular risk. There are conflicting
Laurence Klotz +3 more
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Gonadotropin-releasing hormone (GnRH) is central to the control of the entire hypothalamic-pituitary-gonadal axis. Manipulation of GnRH, in turn, regulates pituitary response and ovarian hormone production.
Farrah L. Saleh, M.D. +1 more
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