Results 241 to 250 of about 1,678,607 (395)

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

Targeting CRHR1 Signaling in Experimental Infantile Epileptic Spasms Syndrome: Evidence for Route-Dependent Efficacy. [PDF]

Children (Basel)
Chachua T, Yum MS, Chern CR, Vieira K, Velíšková J, Velíšek L.   +5 more
europepmc   +1 more source

Growth Hormone Receptor Antagonist [PDF]

, 2020
openaire   +1 more source

Erythrocyte Antibodies in AIDS are associated with mycobacteriosis and hypergammaglobulinemia [PDF]

, 1990
A. Matuschke, AP Rapoport, B. Gathof, B. Heinrich, F. -D. Goebel, FJ Raal, J Lelie van der, J. R. Bogner, L Morris, LI Zon, LI Zon, M Adams, MH McGinniss, P Zauber, PT Toy, PT Toy, PY Lepennec, R Perricone, U. Bäcker, V Daniel, Y Inada, Y Schoenfeld   +21 more
core   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

The intricate interplay between circadian rhythm, androgen signaling, hormone therapy, and cellular senescence in prostate cancer. [PDF]

Cancer Metastasis Rev
Heidari Horestani M, Baniahmad A.
europepmc   +1 more source

Melanin-concentrating hormone receptor 1 antagonists: Synthesis, structure–activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

, 2011
Shizuo Kasai, Masahiro Kamaura, Makoto Kamata, Kazuyoshi Aso, Hitomi Ogino, Yoshihide Nakano, Kaoru Watanabe, Tomoko Kaisho, Michiko Tawada, Yasutaka Nagisa, Shiro Takekawa, Koki Kato, Nobuhiro Suzuki, Yuji Ishihara   +13 more
openalex   +1 more source

Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring

Advanced Science, EarlyView.
Scars exhibit vascular abnormal alterations, including upregulated NRP1 expression in endothelial cells, increased vascular density and branching, compromised vessel wall integrity, and incomplete pericyte coverage. Therapeutic targeting of NRP1 through hydrogel spray delivery offers a promising approach to normalize aberrant vasculature and prevent ...
Yu Wang, Xin Zhou, Min Liu, Meimei Huang, Peirong Chen, Xinying Li, Fangchao Xue, Wenyan Zhao, Di Liu, Lang Li, Yuangang Lu, Wen Zeng   +11 more
wiley   +1 more source

The Involvement of the Peptidergic Systems in Breast Cancer Development. [PDF]

Cancers (Basel)
Sánchez ML, Robinson P, Italia Z, Hoang T, Muñoz M, Coveñas R.   +5 more
europepmc   +1 more source

Comparison of the ultrashort gonadotropin-releasing hormone agonist-antagonist protocol with microdose flare -up protocol in poor responders: a preliminary study

, 2010
Bülent Berker, Candan İltemir Duvan, Cemil Kaya, Ruşen Aytaç, Hakan Şatıroğlu   +4 more
openalex   +1 more source