Peifu Wang, Jilai Li, Shi Qiu, Honfeng Wen, Jichen DuDepartment of Neurology, Aerospace Center Hospital, Peking University Aerospace Clinical College, Beijing, People’s Republic of ChinaBackground and purpose: Published data on the relationship of ...
Wen H, Wang P, Li J, Qiu S, Du J
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CD4+ Tregs Drive Post‐Ischemic Sprouting Angiogenesis via Endothelial YY1/MAML1 Reactivation
ABSTRACT Microvascular complications of diabetes are chronic diseases of small vessels. We previously found that CD4+ regulatory T‐cells (Tregs) are markedly reduced in type 2 diabetes (T2D) after ischemic injury in both mice and humans, and that Treg deficiency in immunodeficient mice impairs vascular regeneration.
Hang Qu +10 more
wiley +1 more source
Successful Pregnancies Following Hormone Replacement Therapy in a Patient with Premature Ovarian Failure: A Case Report [PDF]
Premature ovarian failure is a serious life-changing condition that affects young women, remains an enigma and the researcher’s challenge. Spontaneous pregnancy in a patient with POF is uncommon.
SUNIL KUMAR K.S. +2 more
doaj
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
Understanding Attitudes of Older Women toward Hormone Replacement Therapy
BackgroundCounseling women facing the decision to initiate, continue, or discontinue hormone replacement therapy represents a major challenge for providers.
Buist, Diana SM +5 more
core +1 more source
G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang +9 more
wiley +1 more source
Protocol to assess risk of venous thromboembolism associated with use of hormone replacement therapy in real world settings: two nested case-control studies in primary care [PDF]
Hormone replacement therapy (HRT) is used to help women suffering from menopausal symptoms. Although effective, the therapy may have a rare but serious side effect – an increased risk of venous thromboembolism (VTE).
Vinogradova, Yana +3 more
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HORMONE REPLACEMENT THERAPY IN POSTMENOPAUSE ANDCARDIOVASCULAR DISEASES
BACKGROUND Cardiovascular diseases are the leading cause of morbidity and mortality for adultwomen in developed countries. Several studies report the existence of a gender differencein the use of diagnostic and therapeutic procedures for cardiovascular ...
Barbara Gužič Salobir
doaj
This study demonstrates that transcription factor androgen receptor (AR) directly binds the LF promoter, driving lactoferrin overexpression to promote ferritin (FTH1/FTL) upregulation and inhibit p53‐ALOX12‐mediated ferroptosis in prostate cancer. Lactoferrin could be a new potential therapeutic target in prostate cancer.
Can Liu +18 more
wiley +1 more source
Current trends in hormone replacement therapy: perceptions and usage
OBJECTIVE: To determine whether physicians' confidence in the use of hormone replacement therapy (HRT) for climacteric symptoms has been affected by the negative media interpretation of data from landmark studies investigating HRT usage such as the Women'
Birkhäuser, M H, Reinecke, I
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