Utilisation of hormone replacement therapy in Arab countries: a systematic review. [PDF]
Al Zadjali N +3 more
europepmc +1 more source
This study demonstrates that iron overload triggers widespread chromatin compaction and transcriptional repression in human granulosa cells, recapitulating features of endometriosis. The epigenetic reprogramming is orchestrated by a TFEB‐SOX4‐SWI/SNF axis, with SOX4 acting as a central, dosage‐sensitive regulator.
Feifei Li +15 more
wiley +1 more source
Reproductive Longevity: Innovative Approaches Beyond Hormone Replacement Therapy. [PDF]
Jugulytė N, Bartkevičienė D.
europepmc +1 more source
Menopause and hormone-replacement therapy: Part 2. Hormone-replacement therapy regimens
S, Ratner, D, Ofri
openaire +3 more sources
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma +17 more
wiley +1 more source
Hormone replacement therapy and the risk of achalasia in postmenopausal women: A nationwide cohort study. [PDF]
Oh MJ +8 more
europepmc +1 more source
Polyelectrolyte Design Principles for Electrophoretic Drug Delivery
Structure–property–function mapping of polyelectrolytes reveals how composition and nanoscale order control on‐demand electrophoretic drug transport. Charge density quantified under implant‐relevant conditions shows that encapsulation limits swelling, enabling high effective charge density.
Helena Saarela Unemo +8 more
wiley +1 more source
Hormone Replacement Therapy and Cardiovascular Outcomes by Race and Ethnicity: MESA (Multi-Ethnic Study of Atherosclerosis). [PDF]
Flynn S +5 more
europepmc +1 more source
Trained Memory of Uterine Macrophages Improves Subsequent Pregnancy Outcomes
This study identifies that pregnancy imprints a durable, pregnancy‐specific form of trained immune memory in uterine macrophages, marked by the emergence of LILRB3+/PIR‐B+ cells that expand across gestations, acquire a tolerogenic and metabolically rewired phenotype, and actively protect against inflammatory pregnancy loss in mice.
Jing Wang +8 more
wiley +1 more source
The impact of hormone replacement therapy on cardiovascular health in postmenopausal women: a narrative review. [PDF]
Khalifey HT +9 more
europepmc +1 more source

