Results 181 to 190 of about 3,481,061 (289)

Spontaneous conception and successful live birth during hormone replacement therapy in a patient with iatrogenic premature ovarian insufficiency: a case report. [PDF]

Front Med (Lausanne)
Lee JM, Yang JS, Park JE, Baek JC, Jo JY, Jo HC.   +5 more
europepmc   +1 more source

Non‐Invasive Assessment of Perineural Invasion Density: A Novel Marker for Prognosis and Treatment Stratification in Prostate Cancer

Advanced Science, EarlyView.
This study establishes perineural invasion density (PNID) as a superior prognostic marker in prostate cancer, outperforming conventional perineural invasion in predicting biochemical recurrence and radiographic progression. Concurrent β–blocker use is associated with favorable outcomes exclusively in High–PNID patients. An MRI–based deep learning model
Bohao Liu, Long Zhang, Weian Zhu, Meng Yang, Xiang Liu, Xiaoyang Li, Peng Qin, Zhengxu Lin, Qian Cai, Jiayu Zheng, Xiao Zhao, Chen Zou, Xuan Wen, Longhao Xu, Daqin Wu, Lin Zhang, Cuilian Zhang, Kaiwen Li, Chunhui Wang, Wenlong Zhong, Yun Luo   +20 more
wiley   +1 more source

Long-Term Oncological Implications of Hormone Replacement Therapy in Women With Hypogonadotropic Hypogonadism: A Propensity-Matched Study. [PDF]

Cureus
Eidbo S, Nana M, King S, Barnett M, Mayo R.   +4 more
europepmc   +1 more source

Single‐Cell Insights Into Pathogenic Profile of Orchitis and SREBP2‐Associated Cholesterol Dysregulation in Spermatogenic Failure

Advanced Science, EarlyView.
A first single‐cell atlas of human orchitis reveals coordinated germ‐cell loss, somatic niche dysfunction, and immune‐metabolic remodeling. Aberrant SREBP2 activation in testicular somatic cells emerges as a central pathogenic node, while Fatostatin‐mediated inhibition of the SREBP pathway improves spermatogenesis, fibrosis, and lipid accumulation in a
Yanlin Tang, Qiaoling Jiang, Yuwen Liu, Wenxiu Zhang, Lina Cui, Xiaojian Lu, Ziyan Zhuang, Jianxing Cheng, Songzhan Gao, Yangyi Fang, Kai Hong, Jie Qiao, Xiaoyan Wang, Hui Jiang, Zhe Zhang, Jingtao Guo, Qiang Liu   +16 more
wiley   +1 more source

Real-world study on the effectiveness and breast safety analysis of hormone replacement therapy during menopause. [PDF]

Front Med (Lausanne)
Wang Y, Liu Y, Zeng J, Wang M, Li Y, Wu Y, Gao J, Chen X.   +7 more
europepmc   +1 more source

MetaPaCS: A Novel Meta‐Learning Framework for Pancreatic Cancer Subtype Identification

Advanced Intelligent Systems, EarlyView.
We have developed MetaPaCS, an ensemble meta‐learning framework for reliable prediction of pancreatic cancer subtypes with high accuracy. MetaPaCS is capable of capturing subtype‐specific distinct gene expression patterns and drug‐disease associations for pancreatic cancer.
Nick B. Peterson, Mengtao Sun, Xinchao Wu, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Utilisation of hormone replacement therapy in Arab countries: a systematic review. [PDF]

Front Glob Womens Health
Al Zadjali N, Tabche C, Atwan Z, Rawaf S.   +3 more
europepmc   +1 more source

Reverse Haptic Alerting: Human‐Centered Intelligent Systems That Turn Chemical and Biomedical Signals Into Felt Cues

Advanced Intelligent Systems, EarlyView.
Wearable sensors usually warn through sight or sound, channels that become unreliable under protective equipment or in noise. Reverse haptic alerting inverts this flow: Stimuli‐responsive materials convert chemical and biological signals into cues felt through the skin, while a machine‐learned digital twin of tactile perception personalizes the body ...
Hwanhee Yoo, Shin Hum Cho, Ku Kang, Yoon Jeong Jang, Chan‐Mo Yang, Doo‐Hee Lee   +5 more
wiley   +1 more source

Reproductive Longevity: Innovative Approaches Beyond Hormone Replacement Therapy. [PDF]

Medicina (Kaunas)
Jugulytė N, Bartkevičienė D.
europepmc   +1 more source

COX14 Variants Are Associated With Mitochondrial Complex IV Deficiency Nuclear Type 10 (MC4DN10)

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT COX14 encodes a transmembrane protein essential for cytochrome c oxidase (COX) complex assembly. A homozygous missense variant in COX14 was reported in three siblings from a single consanguineous family with severe, fatal infantile mitochondrial complex IV deficiency nuclear type 10 (MC4DN10; MIM# 619053).
Elias K. Awad, Emily Waskow, Hari Tunuguntla, Joseph Spinner, Hanna J. Tadros, Lisa T. Emrick, Daniel G. Calame, Fernando Scaglia   +7 more
wiley   +1 more source