Results 191 to 200 of about 258,704 (366)

Application of humanized mice in the safety experiments of antibody drugs

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The graphical abstract of this review highlights the critical role of humanized mice in the safety evaluation of antibody drugs. First, the inherent immunogenicity of antibody drugs can lead to the production of antidrug antibodies and hypersensitivity reactions on repeated administration.
Zhimin Sun   +9 more
wiley   +1 more source

HORMONE REPLACEMENT THERAPY AND BREAST CANCER – NEWS ANDRECOMMENDATION

open access: yesZdravniški Vestnik, 2008
BACKGROUND HT should be considered only when an indication for therapy has been clearly identified,contraindications ruled out, and the potential individual benefits and risks adequatelydiscussed with the women so that an informed decision can be made ...
Marjetka Uršič Vrščaj   +5 more
doaj  

Neutrophil‐to‐lymphocyte and monocyte‐to‐lymphocyte ratios as inflammatory markers in the assessment of glycemic status in diabetic patients of Asir region

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Neutrophil‐to‐lymphocyte ratio (NLR) and monocyte‐to‐lymphocyte ratio (MLR) were investigated as potential markers. A total of 3545 subjects were included in the analysis retrospectively. Adult men and women with impaired glucose metabolism were assessed. NLR and MLR may help assess inflammation in individuals with impaired glucose metabolism. Abstract
Ayed A. Dera   +11 more
wiley   +1 more source

Hormone replacement therapy in postmenopause - where we stand?

open access: yesZdravniški Vestnik, 2007
Background: The findings of most relevant randomized clinical studies such as HERS, WHI and MWS, performed in the last decade have shown that hormonal replacement therapy (HRT) users are at increased risk for the development of breast cancer, stroke and ...
Damir Franić
doaj  

Hormone replacement therapy and risk of epithelial ovarian cancer [PDF]

open access: hybrid, 1999
David M. Purdie   +7 more
openalex   +1 more source

Animal models of lung cancer: Phenotypic comparison of different animal models of lung cancer and their application in the study of mechanisms

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Grafts used to construct lung cancer animal models come from various sources, primarily cell lines, patient‐derived tumor tissues, and circulating tumor cells. Based on the sources of grafts and research objectives, lung cancer animal models can be categorized into several types: chemical‐induced models, orthotopic transplantation models, heterotopic ...
Zixuan Yang   +7 more
wiley   +1 more source

Hormone Replacement Therapy after Prophylactic Adnexectomy

open access: yesHereditary Cancer in Clinical Practice, 2005
This Pascale   +5 more
doaj   +1 more source

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