Results 31 to 40 of about 113,726 (260)

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

HORMONE REPLACEMENT THERAPY AND CANCER

open access: yesZdravniški Vestnik, 2003
Background. Sex steroids are not known to damage DNA directly. They can stimulate or inhibit cell proliferation, and thus can modulate tumor developmental progression.Results.
Marjetka Uršič Vrščaj
doaj  

Estrogenic/Progestin therapy and the development of Vestibular Schwannoma: A systematic review and meta-analysis

open access: yesBrazilian Journal of Otorhinolaryngology
Objective: Compare the risk of developing Vestibular schwannoma in patients prescribed Hormone Therapy (HT). Methods: We performed a systematic review in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis (PRISMA), the
Maria Vitória Graça Couto de Campos Amaral   +1 more
doaj   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

open access: yesMolecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant   +7 more
wiley   +1 more source

OSTEOPOROSIS AND HORMONE REPLACEMENT THERAPY

open access: yesZdravniški Vestnik, 2008
BACKGROUND Osteoporosis affects almost every other woman after menopause. Fractures due to osteoporosis are a significant cause of disability and death, therefore we try to prevent themwith antiosteoporotic medications.Hormone replacement therapy (HRT ...
Tomaž Kocjan, Damir Franić
doaj  

Effects of Growth Hormone Replacement Therapy on Bone Mineral Density in Growth Hormone Deficient Adults: A Meta-Analysis

open access: yesInternational Journal of Endocrinology, 2013
Objectives. Growth hormone deficiency patients exhibited reduced bone mineral density compared with healthy controls, but previous researches demonstrated uncertainty about the effect of growth hormone replacement therapy on bone in growth hormone ...
Peng Xue, Yan Wang, Jie Yang, Yukun Li
doaj   +1 more source

Postmenopausal hormonal therapy: Current status

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Many trials of the pros and cons of postmenopausal hormone replacement therapy have been done and this treatment has evolved over time. Here, we present a review and current status of this therapy.
V P Jyotsna
doaj   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

GAD65 Antibody ELISA With Extended Reportable Range: Validation and Guidance for Neurological Practice

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To (1) validate GAD65‐ELISA detection and quantification for type 1 diabetes mellitus and autoimmune neurological diagnoses, (2) correlate ELISA results (reference range < 5 IU/mL) with established radioimmunoprecipitation assay (RIA; ≤ 0.02 nmol/L), and (3) define ELISA clinical utility and pitfalls.
Andrew McKeon   +11 more
wiley   +1 more source

Treatment of hypoparathyroidism (HypoPT): Position Statement of the Expert Group for Polish Society of Endocrinology — update 2026

open access: yesEndokrynologia Polska
Hypoparathyroidism (HypoPT) remains the last “classic” endocrine deficiency hormone disorder not routinely treated with hormone replacement. In November 2023, European Medicines Agency (EMA), and in August 2024, Food and Drug Administration (FDA ...
Waldemar Misiorowski   +6 more
doaj   +1 more source

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