Results 61 to 70 of about 113,726 (260)

HORMONE REPLACEMENT THERAPY AND VENOUS THROMBOEMBOLISM

Zdravniški Vestnik, 2008
BACKGROUND Oral hormone replacement therapy (HRT) is associated with 2- to 4-fold increased riskof venous thromboembolism (VTE). Therefore, all women commencing HRT should becounselled about the risk of VTE, signs and symptoms of VTE and measures for ...
Nina Vene
doaj  

Fezolinetant - a potential alternative to hormone replacement therapy for menopausal women

Journal of the Pakistan Medical Association
Dear Editor, Menopause is a significant milestone in a woman's life, marking the end of the reproductive cycle due to the depletion of all the ovarian follicles.
Hassan Mehmood, Komal Zulfiqar, Ahsanat Fatima   +2 more
doaj   +1 more source

An Ion‐Based Strategy Toward Synergistic Surface Functionalization Combining the Osteogenic Properties and NIR‐Mediated Antibacterial Activity of PEEK

Advanced Materials, EarlyView.
A multifunctional bioactive PEEK‐based implant (Mn@p/MBG‐SPEEK) is engineered to combat implant‐associated infections while promoting osteogenesis. The hybrid surface activates PI3K/Akt/mTOR and AP‐1 signaling pathways for osteogenic differentiation, while Mn coordination induces electronic coupling that narrows the HOMO‐LUMO energy gap and enhances ...
Zhiyan Xu, Ondřej Adam, Marek Doubrava, Ana M. Beltrán, Ivo Dlouhý, Xin Liu, Baiyan Sui, Aldo R. Boccaccini   +7 more
wiley   +1 more source

Changes in the profile of lipoprotein subfractions associated with hormone replacement therapy

Arquivos Brasileiros de Cardiologia, 2001
OBJECTIVE: To report the effects of 2 regimens of hormone replacement therapy during the postmenopausal period on the profile of the major lipoprotein subfractions (HDL, LDL, and VLDL). METHODS: We carried out a cohort study in 38 postmenopausal patients
José Luiz da Costa Vieira, Marcos Emanuel W. Gomes, Áurea Beltrão de Almeida, Emílio H. Moriguchi   +3 more
doaj   +1 more source

Biointegrated Battery‐Based Electroceuticals

Advanced Materials, EarlyView.
Biointegrated batteries go beyond passive power to serve as active therapeutic platforms for delivering programmable electrical cues and bioactive agents. This review examines their mechanisms and applications and provides a framework to guide battery‐based therapeutic design and clinical translation.
Yan Zhou, Zhilian Yue, Zhiqi Chen, Danming Chao, Xiaoteng Jia, Gordon Wallace, Caiyun Wang   +6 more
wiley   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Adipocyte‐Derived Leptolin Enhances Energy Expenditure and Prevents Obesity

Advanced Science, EarlyView.
We identified a novel adipokine, which we named leptolin. In humans, leptolin levels in white adipose tissue were positively correlated with exercise and negatively associated with body mass index. We observed elevated leptolin in serum from athletes and lower leptolin in serum from obese individuals.
Jiarui Liu, Bingwei Wang, Zhijie Su, Xiaoxv Han, Miao He, Yun Zhao, Yujia Hou, Daotong Li, Weiguang Zhang, Lihua Qin, Ke Wang, Yanchun Li, Yi Yan, Siwang Yu, Xiaoshuai Huang, Tairan Yuwen, Jianyuan Luo, Ruimao Zheng   +17 more
wiley   +1 more source

Remarkable change in age-specific breast cancer incidence in the Swiss canton of Geneva and its possible relation with the use of hormone replacement therapy

BMC Cancer, 2006
Background This article aims to explain the reasons for the remarkable change in age of breast cancer occurrence in the Swiss canton of Geneva. Methods We used population-based data from the Geneva cancer registry, which collects information on method of
Wespi Yves, Fioretta Gérald, Verkooijen Helena M, Morabia Alfredo, Bouchardy Christine, Schäfer Peter   +5 more
doaj   +1 more source

Taking hormone replacement therapy

BMJ, 2003
Women and health professionals should make the decision jointly and review it periodically In the United Kingdom women at midlife are facing the decision whether to take hormone replacement therapy or not. The backdrop to this includes widespread discussion in the media of hormone replacement therapy, high levels of lay awareness, a medical ...
openaire   +3 more sources

Hormone Replacement Therapy: An Update [PDF]

The Journal of Obstetrics and Gynecology of India, 2012
Ever since menopause was causally linked to several symptoms and disease processes, the concept of hormone replacement therapy (HRT) took root and was widely practiced over half a century. We have witnessed the rise and fall of the HRT during these years.
openaire   +2 more sources