Results 71 to 80 of about 3,110,681 (290)

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Thyroid Hormone Therapy for Potential Heart Donors: A Comprehensive Review of Clinical Trials

Biomedicines
Background: Due to neurohormonal disturbances that occur following brain death, thyroid hormone therapy has been proposed as a means to enhance cardiac function in brain-dead organ donors.
Mushood Ahmed, Eeshal Zulfiqar, Sonia Hurjkaliani, Aimen Shafiq, Hafsa Arshad Azam Raja, Areeba Ahsan, Aemen Kamran, Laveeza Fatima, Amna Nadeem, Muhammad Abdullah Naveed, Faizan Ahmed, Hritvik Jain, Tallal Mushtaq Hashmi, Muath Baniowda, Mansimran Singh Dulay, Sivaram Neppala, Himaja Dutt Chigurupati, Ali Hasan, Peter Collins, Raheel Ahmed   +19 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Ductal carcinoma In-Situ in turner syndrome patient undergoing hormone replacement therapy: A case report [PDF]

, 2016
Turner’s syndrome is a rare congenital disease which affects about 1 in every 2500-3000 live-born females. This happens due to chromosomal abnormalities in a phenotypic female, causing increased gonadotropin concentrations and low concentrations of ...
Matemavi, Praise; Department of Surgery, New York Presbyterian Queens Hospital/Weill Cornell Medical College, New York, Maizlin, Ilan; Department of Surgery, New York Presbyterian Queens Hospital/Weill Cornell Medical College, New York, Bawa, Rashmi; Department of Surgery, Pine Health Services, Maine, Sung, Kap-Jae; Department of Surgery, New York Presbyterian Queens Hospital/Weill Cornell Medical College, New York   +3 more
core   +3 more sources

Prevention and treatment of venous thromboembolism during HRT: current perspectives

International Journal of General Medicine, 2014
Hannelore Rott Coagulation Center Rhine-Ruhr, Duisburg, Germany Abstract: Many large trials in the past 15 years have proven an increased risk of vascular complications in women using oral, mostly non-bioidentical, hormone therapy.
Rott H
doaj  

Non-conventional hormone therapy - Tissue-specific Tibolone-Caution

Journal of Mid-Life Health, 2010
Objectives: The present retrospective study was undertaken to assess safety profile of long term Tibolone therapy when one of my patients developed carcinoma breast. Methods: Fifty patients who were put on Tibolone were studied as regards the indication
Jyotsna Potdar
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A reassessment of the cost-effectiveness of hormone replacement therapy in Sweden – results based on the Women’s Health Initiative randomised controlled trial [PDF]

The cost-effectiveness of hormone replacement therapy (HRT) based on a societal perspective is reassessed based on new medical evidence found in the Women’s Health Initiative (WHI).
Jönsson, Bengt, Borgström, Fredrik, Zethraeus, Niklas, Kanis, John   +3 more
core  

Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.

, 2004
This chapter about antithrombotic therapy for coronary artery disease (CAD) is part of the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy: Evidence Based Guidelines. Grade 1 recommendations are strong and indicate that the benefits do,
Christopher M. O'Connor, O'Connor, Christopher M, Meade, Thomas W, Guyatt, Gordon H, Becker, Richard C, David A. Vorchheimer, Harrington, Robert A, Michael Ezekowitz, Ezekowitz, Michael, Thomas W. Meade, Vorchheimer, David A, Gordon H. Guyatt, Robert A. Harrington, Richard C. Becker   +13 more
core   +1 more source

Treating allergic bronchopulmonary aspergillosis with hormone therapy: natural disease course, regimens, compliance, and outcomes

Frontiers in Medicine
ObjectiveCurrent guidelines lack information on the natural course and prognosis of allergic bronchopulmonary aspergillosis (ABPA). In this retrospective study, the natural course of ABPA was evaluated in patients treated with hormone therapy.Materials ...
Qiyin Wu, Yaping Huang, Jiachao Qi, Miaofen Hu, Huixue Zeng, Weiliang Zhang, Liangji Zhang   +6 more
doaj   +1 more source