Results 81 to 90 of about 713,905 (310)

Coronary Calcification and Hormones

, 2011
The pathogenesis of coronary artery calcification and its role in atherogenesis has not been completely understood but is a new focus of interest in experimental and clinical research.
Henein, Michael Y,, Koulaouzidis, George,, George Koulaouzidis, Michael Henein   +3 more
core   +1 more source

Neuropeptide therapeutics to repress lateral septum neurons that disable sociability in an autism mouse model

Cell Reports Medicine
Summary: Confronting oxytocin and vasopressin deficits in autism spectrum disorders and rare syndromes brought promises and disappointments for the treatment of social disabilities.
Amélie M. Borie, Yann Dromard, Prabahan Chakraborty, Pierre Fontanaud, Emilie M. Andre, Amaury François, Pascal Colson, Françoise Muscatelli, Gilles Guillon, Michel G. Desarménien, Freddy Jeanneteau   +10 more
doaj   +1 more source

Linking Mitochondria to Synapses: New Insights for Stress-Related Neuropsychiatric Disorders

Neural Plasticity, 2016
The brain evolved cellular mechanisms for adapting synaptic function to energy supply. This is particularly evident when homeostasis is challenged by stress.
Freddy Jeanneteau, Margarita Arango-Lievano   +1 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

The BES1/BZR1 transcriptional factor SlBES2 regulates photosynthetic apparatus in tomato fruit

BMC Plant Biology
Background Fruit photosynthetic apparatus development comprises a series of biological processes which is essential in determining fruit development and quality formation.
Ming Huang, Wenjing Liu, Deding Su, Ghassen Abid, Baowen Huang, Zhengguo Li   +5 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Hormones surrenaliennes : physiologie et exploration biologique

, 2015
-Physiologie surrenale-Hormones corticosurrenaliennes-Hormones médullosurrenaliennes-Pathologies ...
Coulibaly André (1263195)
core   +1 more source

A conserved fungal effector disturbs Ca2+ sensing and ROS homeostasis to induce plant cell death

Nature Communications
Acting as a major Ca2+ sensor, calmodulin (CaM) activates target proteins to regulate a variety of cellular processes. Here, we report that CaM–target binding is disturbed by a fungal virulence effector PdCDIE1 (Penicillium digitatum Cell Death-Inducing ...
Yunlong Lin, Chan Xu, Lili Li, Liqin Fan, Rui Li, Jiaxin He, Hongli Li, Wei Deng, Zhensheng Kang, Zhengguo Li, Yulin Cheng   +10 more
doaj   +1 more source