Results 81 to 90 of about 893,278 (399)

A retinoscopic survey of 333 horses and ponies in the UK [PDF]

, 2014
Introduction: Ophthalmic examination in the horse is generally limited to crude assessment of vision and screening for ocular lesions. The refractive state of equine eyes and the potential impact on vision and performance requires further ...
Chung, Coile, Corboy, Davidson, Duval, Evans, Flitcroft, Gaiddon, Gordon, Graham, Grinninger, Harman, Howlett, Kinney, McClatchey, McMullen, Michau, Miller, Murphy, Murphy, Mutti, Norton, Ofri, Owens, Rose, Rosenfield, Rull-Cotrina, Saunders, Sekuler, Sivak, Smith, Svaldenienė, Timney, Weale, Wong, Wright, Young, Young, Zadnik   +38 more
core   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Nasal and tracheobronchial nitric oxide production and its influence on oxygenation in horses undergoing total intravenous anaesthesia

BMC Veterinary Research, 2022
Background The present study aimed to investigate the effect of endotracheal intubation on nasal and tracheal endogenous NO concentrations, gas exchange and oxygenation in horses undergoing general anaesthesia.
Henriette L. Wilkens, Stephan Neudeck, Sabine B. R. Kästner   +2 more
doaj   +1 more source

Impact of Different Diagnostic Procedures on Diagnosis, Therapy, and Outcome in Horses with Headshaking: Recommendations for Fast-Track Advanced Diagnostic and Therapeutic Protocols

Animals, 2022
Most horses affected by headshaking (HS) are diagnosed with idiopathic trigeminal-mediated headshaking (i-TMHS) when no underlying disease is found. Diagnosis is made by the exclusion of differentials considering history, clinical signs, and diagnostic ...
Tanja Kloock, Maren Hellige, Anke Kloock, Karsten Feige, Tobias Niebuhr   +4 more
doaj   +1 more source

Characterisation of the Faecal Bacterial Community in Adult and Elderly Horses Fed a High Fibre, High Oil or High Starch Diet Using 454 Pyrosequencing

PLoS ONE, 2014
Faecal samples were collected from seventeen animals, each fed three different diets (high fibre, high fibre with a starch rich supplement and high fibre with an oil rich supplement).
K. Dougal, Gabriel de la Fuente, Pat A. Harris, S. Girdwood, E. Pinloche, Raymond J. Geor, Brian D Nielsen, Harold C. Schott, S. Elzinga, C. J. Newbold   +9 more
semanticscholar   +1 more source

A bioinformatics screen identifies TCF19 as an aggressiveness‐sustaining gene in prostate cancer

Molecular Oncology, EarlyView.
Gene expression meta‐analysis in multiple prostate cancer patient cohorts identifies Transcription factor 19 (TCF19) as an aggressiveness‐sustaining gene with prognostic potential. TCF19 is a gene repressed by androgen signaling that sustains core cancer‐related processes such as vascular permeability or tumor growth and metastasis.
Amaia Ercilla, Jana R. Crespo, Saioa Garcia‐Longarte, Marta Fidalgo, Sara del Palacio, Natalia Martin‐Martin, Onintza Carlevaris, Ianire Astobiza, Sonia Fernández‐Ruiz, Marc Guiu, Laura Bárcena, Isabel Mendizabal, Ana M. Aransay, Mariona Graupera, Roger R. Gomis, Arkaitz Carracedo   +15 more
wiley   +1 more source

Anaesthetic Management of a 1-Month-Old Puppy Undergoing Lateral Thoracotomy for Vascular Ring Anomaly Correction

Case Reports in Veterinary Medicine, 2011
A 1-month-old male flat-coated retriever was anaesthetized for correction of oesophageal constriction caused by a vascular ring anomaly. Anaesthesia was uneventfully induced with intravenous fentanyl, diazepam, and propofol and maintained with isoflurane
Olga Martin Jurado, Martina Mosing, Regula Bettschart-Wolfensberger   +2 more
doaj   +1 more source

Faecal Microbiota of Forage-Fed Horses in New Zealand and the Population Dynamics of Microbial Communities following Dietary Change

PLoS ONE, 2014
The effects of abrupt dietary transition on the faecal microbiota of forage-fed horses over a 3-week period were investigated. Yearling Thoroughbred fillies reared as a cohort were exclusively fed on either an ensiled conserved forage-grain diet (“Group ...
K. A. Fernandes, S. Kittelmann, C. Rogers, E. Gee, C. Bolwell, E. Bermingham, D. Thomas   +6 more
semanticscholar   +1 more source

Effects of Single-Dose Prucalopride on Intestinal Hypomotility in Horses: Preliminary Observations [PDF]

, 2017
Abnormalities of gastrointestinal motility are often a challenge in horses; however, the use of prokinetic drugs in such conditions must be firmly established yet.
Bassotti, G., Faillace, Vanessa, Fettucciari, K, Fratini, Margherita, Laus, Fulvio, Paggi, Emanuele, Spaterna, Andrea, Tesei, Beniamino   +7 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source