Results 91 to 100 of about 7,369,841 (409)

Impact of new‐onset and preexisting neurological disorders in COVID‐19 patients

Brain and Behavior, 2023
Background and Purpose Coronavirus disease (COVID‐19) is still considered a global pandemic. The prognosis of COVID‐19 patients varies greatly. We aimed to assess the impact of preexisting, chronic neurological diseases (CNDs) and new‐onset acute ...
Sarah Lindemann, Markus Böhm, Falk Gonnert, Julian Bösel, Roger Schubert, Rita Musleh, Albrecht Günther   +6 more
doaj   +1 more source

Association of geriatric nutritional risk index with all-cause hospital mortality among elderly patients in intensive care unit

Frontiers in Nutrition, 2023
BackgroundMalnutrition is associated with poor outcomes for geriatric patients in intensive care unit (ICU). It is important to identify patients at risk of malnutrition and provide individual nutrition support. The assessment of malnutrition risk is not
Jiang-Chen Peng, Yi-Wei Zhu, Shun-Peng Xing, Wen Li, Yuan Gao, Wen-Wen Gong   +5 more
doaj   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

Molecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li, Zhijie Cao, Haiyan Xing, Zhenya Xue, Wenbing Liu, Jiayuan Chen, Yihan Mei, Runxia Gu, Hui Wei, Shaowei Qiu, Min Wang, Qing Rao, Jianxiang Wang   +12 more
wiley   +1 more source

A simple test‐based frailty index to predict survival among cancer patients with an unplanned hospitalization: An observational cohort study

Cancer Medicine, 2021
Background Frailty is a state of increased vulnerability to stressors, and predicts risk of adverse outcomes, such as mortality. Frailty can be defined by a frailty index (FI) using an accumulation of deficits approach.
Timothy Hembree, Olga Theou, Sarah Thirlwell, Richard R. Reich, Biwei Cao, Marina Sehovic, Misbahuddin Syed, Neha Verma, Thu‐Cuc Nguyen, Dinesh Keerty, Jaqueline Wesolow, Viktoriya Koverzhenko, Martine Extermann, Jessica Huang, Asha Ramsakal   +14 more
doaj   +1 more source

Safety and Efficacy of Hospital Utilization of Tranexamic Acid in Civilian Adult Trauma Resuscitation [PDF]

, 2020
Introduction: Patients with trauma-induced coagulopathies may benefit from the use of antifibrinolytic agents, such as tranexamic acid (TXA). This study evaluated the safety and efficacy of TXA in civilian adults hospitalized with traumatic hemorrhagic ...
Borger, Rodney, Chandwani, Deepak, Comunale, Mark E., Dong, Fanglong, Inaba, Kenji, Lowe, Andrew, Neeki, Michael, Powell, Joe, Quispe, Juan, Rabiei, Massoud, Salameh, Joseph, Toy, Jake, Vara, Richard, Wong, David   +13 more
core  

Effect of individual-level and socioeconomic factors on long-term survival after cataract surgery over a 30-year period [PDF]

, 2017
Purpose: To evaluate survival and the risk for mortality after cataract surgery in relation to individual-level and socioeconomic factors in Scotland over 3 decades. Setting: Linked healthcare data, United Kingdom.
Blundell, Charlson, Dickey, Fong CS-u, Mitchell, Fong CS-u, Mitchell, Greenberg, Levin, Quan, Smith, Tseng   +9 more
core   +2 more sources

Hospitalization Rates and In-Hospital Mortality Among Centenarians [PDF]

Archives of Internal Medicine, 2012
The number of Americans at least 100 years old is expected to grow dramatically over the coming years. In December 2010, 71 991 centenarians lived in the United States, almost double the number there were 20 years ago.1, 2 By 2050, the number of centenarians is expected to reach 601 000, a 735% increase.2 Despite the growing numbers, the health care ...
Mahendra K. Mandawat, Aditya Mandawat, Anant Mandawat, Mary E. Tinetti   +3 more
openaire   +3 more sources

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Nurse staffing levels, missed vital signs and mortality in hospitals: retrospective longitudinal observational study

Health Services and Delivery Research, 2018
Background: Low nurse staffing levels are associated with adverse patient outcomes from hospital care, but the causal relationship is unclear. Limited capacity to observe patients has been hypothesised as a causal mechanism.
Peter Griffiths, Jane Ball, Karen Bloor, Dankmar Böhning, Jim Briggs, Chiara Dall’Ora, Anya De Iongh, Jeremy Jones, Caroline Kovacs, Antonello Maruotti, Paul Meredith, David Prytherch, Alejandra Recio Saucedo, Oliver Redfern, Paul Schmidt, Nicola Sinden, Gary Smith   +16 more
doaj   +1 more source

Non-invasive positive pressure ventilation in acute hypercapnic respiratory failure: clinical experience of a respiratory ward

Monaldi Archives for Chest Disease, 2004
Background: Although a controlled trial demonstrated that non-invasive positive pressure ventilation (NIV) can be successfully applied to a respiratory ward (RW) for selected cases of acute hypercapnic respiratory failure (AHRF), clinical practice data ...
R. Scala, M. Naldi, I. Archinucci, G. Coniglio   +3 more
doaj   +1 more source