Results 101 to 110 of about 7,369,841 (409)

Clinical characteristics and outcomes of patients with inflammatory and autoimmune rheumatological diseases admitted for intensive care in Colombia

Reumatismo, 2023
Objective. Contemporary studies reporting outcomes of critical care in patients with inflammatory and autoimmune rheumatological diseases are scarce. This study describes 15 years of experience from 2005-2019 in a Colombian referral hospital. Methods.
D.G. Fernández-Ávila, Ó.R. Vargas-Vanegas, L. Galindo-Rozo, Á. García-Peña, Ó. Muñoz-Velandia   +4 more
doaj   +1 more source

Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis

Journal of the American Medical Association (JAMA), 2018
Importance The death of a pediatric patient with sepsis motivated New York to mandate statewide sepsis treatment in 2013. The mandate included a 1-hour bundle of blood cultures, broad-spectrum antibiotics, and a 20-mL/kg intravenous fluid bolus.
Idris V. R. Evans, Gary S. Phillips, Elizabeth R. Alpern, Derek C Angus, M. Friedrich, N. Kissoon, S. Lemeshow, Mitchell M. Levy, M. Parker, Kathleen M. Terry, R. Watson, Scott L. Weiss, J. Zimmerman, Christopher W. Seymour   +13 more
semanticscholar   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn, Cynthea Prima, Tae Min Kim, Soon‐Tae Lee, Kon Chu   +4 more
wiley   +1 more source

Rapid response team: what factors interfere with your performance?

Investigación y Educación en Enfermería, 2018
Objective. Describe the knowledge in the literature related to factors that influence the performance of response teams. Methods. Integrative review of the literature of articles published in Portuguese, English or Spanish between 2006 and 2016.
Aline A. S. Moreira, Rogiane O. Ramos, Anna Beatriz S. Ligório, Karolina D. Junqueira, Krislainy S. Corrêa   +4 more
doaj   +1 more source

The Association Between Etiologies and Mortality in Acute Respiratory Distress Syndrome: A Multicenter Observational Cohort Study

Frontiers in Medicine, 2021
Background: Lung-protective ventilation (LPV) strategies have been beneficial in patients with acute respiratory distress syndrome (ARDS). As a vital part of LPV, positive end-expiratory pressure (PEEP) can enhance oxygenation.
Yan Wang, Linlin Zhang, Xiuming Xi, Jian-Xin Zhou, The China Critical Care Sepsis Trial (CCCST) Workgroup, Bin Du, Li Weng, Tong Li, Meili Duan, Wenxiong Li, Bing Sun, Jianxin Zhou, Jianguo Jia, Xi Zhu, Qingyuan Zhan, Xiaochun Ma, Tiehe Qin, Shouhong Wang, Yuhang Ai, Yan Kang, Xuelian Liao, Xiangyuan Cao, Yushan Wang   +22 more
doaj   +1 more source

Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China

Intensive Care Medicine, 2020
Dear Editor, The rapid emergence of COVID-19 in Wuhan city, Hubei Province, China, has resulted in thousands of deaths [1]. Many infected patients, however, presented mild flu-like symptoms and quickly recover [2]. To effectively prioritize resources for
Qiurong Ruan, Kun Yang, Wenxia Wang, Lingyu Jiang, Jianxin Song   +4 more
semanticscholar   +1 more source

Mechanical Thrombectomy for TRACE‐III‐Eligible Patients With Ischemic Stroke: A Multicenter Retrospective Study Compared to TRACE‐III and TIMELESS Trials

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The results of the TRACE‐III trial demonstrated that tenecteplase (TNK) might be comparable to TNK combined with mechanical thrombectomy (MT) for large vessel occlusion (LVO) stroke within 4.5 to 24 h of onset, as tested in the TIMELESS trial.
Chongyang Huang, Yanru Liu, Jiangang Zhang, Sheng Guan, Tao Quan, Zhen Chen, Xiaojie Fu, Sen Wei, Kaihao Han, Xiaoan Zhou, Chengcheng Zhu, Edgar Samaniego, Yueqi Zhu, Haowen Xu   +13 more
wiley   +1 more source

The relationship between ICU hypotension and in-hospital mortality and morbidity in septic patients

Intensive Care Medicine, 2018
PurposeCurrent guidelines recommend maintaining a mean arterial pressure (MAP) ≥ 65 mmHg in septic patients. However, the relationship between hypotension and major complications in septic patients remains unclear.
K. Maheshwari, B. Nathanson, S. Munson, V. Khangulov, Mitali Stevens, Hussain Badani, A. Khanna, D. Sessler   +7 more
semanticscholar   +1 more source

Observational Study of Tocilizumab in Children With Febrile Infection‐Related Epilepsy Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to assess the efficacy and safety of using tocilizumab in children with febrile infection‐related epilepsy syndrome (FIRES) and explore tocilizumab‐related changes in interleukin (IL)‐6 levels. Methods Patients with FIRES admitted to the Intensive Care Unit (ICU) of Beijing Children's Hospital were retrospectively ...
Yushan He, Jie Wu, Chaonan Fan, Zheng Li, Jun Liu, Kechun Li, Quan Wang, Suyun Qian   +7 more
wiley   +1 more source