Results 211 to 220 of about 8,605,387 (387)

Exome Sequencing Reveals the Genetic Architecture of Non‐syndromic Orofacial Clefts and Identifies BOC as a Novel Causal Gene

Advanced Science, EarlyView.
Nonsyndromic orofacial clefts (NSOFCs) are the most common craniofacial defects. Exome sequencing of 214 sporadic cases sheds new light on its genetic architecture and identifies many candidate pathogenic variants. Furthermore, functional studies establish BOC as a novel causal gene and reveal an unusual two‐locus model of inheritance via the epistatic
Qing He, Min Yu, Yuhua Jiao, Yizhu Xu, Xuqin Liang, Wenbin Huang, Linping Xu, Yuxia Hou, Zhanping Ren, Beile Lyu, Zhenwei Qian, Pengpeng Liu, Jing Zhou, Huimei Huang, Chunyan Yin, Huaxiang Zhao, Yi Ding   +16 more
wiley   +1 more source

4068 Functional Analysis of Rehabilitation Center in General Hospital(Design and Planning)

, 1967
Fui-yu Chin
openalex   +2 more sources

Outcome of planned home and planned hospital births in low risk pregnancies: prospective study in midwifery practices in the Netherlands [PDF]

, 1996
T.A. Wiegers, Marc J.N.C. Keirse, Jouke van der Zee, G.A.H. Berghs   +3 more
openalex   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

Advanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen, Xiaoxiao Meng, Yong Zhu, Dapeng Wang, Mengmeng Wang, Ziyuan Wang, Xue Tian, Jiaxiang Zhang, Zhiying Yue, Zhengfeng Yang, Ruilan Wang   +10 more
wiley   +1 more source

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source

Model Emergency Department Plan in Support of Disaster Relief Efforts in an Urban Community: A Review of Emergency Department Plans of Public Hospitals in Singapore [PDF]

, 1999
Francis Lee Chun Yue, V. Anantharaman
openalex   +1 more source

Epigenetic Activation of CCDC183‐AS1 Promotes Osteoclastogenesis and Prostate Cancer Bone Metastasis Through the FUBP1/LIGHT Axis

Advanced Science, EarlyView.
CCDC183‐AS1 overexpression enhanced the ability of PCa cells to spread to the bone by inducing osteoclastogenesis. Mechanistically, CCDC183‐AS1 interacted with FUBP1 and enhanced its stability, which promoted the transcription of TNFSF14 (LIGHT). Copy number gain‐induced KDM5C epigenetically upregulated CCDC183‐AS1 expression by recruiting TET1 to the ...
Chuandong Lang, Xiangyu Mu, Kun Chen, Xinwen Wang, Yuluo Rong, Jia Wang, Zongcheng Yang, Chi Yin, Yuhu Dai, Jun Xiao, Wenzhi Zhang   +10 more
wiley   +1 more source

PATTERN ANALYSIS OF PLANNING AND MANAGEMENT AT THE RADIOGRAPHIC DEPT. IN HOSPITAL : Planning method by circulation study-1

, 1979
Makoto Yanagisawa, Shoji Imai, Gen TANIGUCHI   +2 more
openalex   +2 more sources

Dual‐Crosslinked Betaine‐Based Amphiphilic Hydrogel as a Promising Vitreous Substitute: Anti‐Adhesion, Anti‐Fouling, and Anti‐Cell Proliferation

Advanced Science, EarlyView.
A novel multiple cross‐linked betaine‐type amphiphilic polymer hydrogels are developed via in situ free radical copolymerization. The resultant formation, named P(SBMA‐co‐AANa) hydrogel, functions as a vitreous substitute and demonstrates superior performance in optical properties, support capacity, and biocompatibility on a vitrectomized rabbit model.
Yuting Cai, Yun Tan, Jian Cao, Xiaoyuan Zhou, Xingyuan Li, Jianghua Li, Chuntai Liu, Yi Zhang, Yun Li   +8 more
wiley   +1 more source

Strategic planning and organizational performance in public health sector: a scoping review. [PDF]

BMC Health Serv Res
Wongsin U, Pannoi T, Prutipinyo C, Maruf MA, Pongpattrachai D, Quansri O, Sattayasomboon Y.   +6 more
europepmc   +1 more source