Results 111 to 120 of about 1,923,093 (282)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

O Sistema de Informação Hospitalar e sua aplicação na saúde coletiva

open access: yesCadernos de Saúde Pública
O trabalho teve como objetivo levantar a produção científica das aplicações dos dados do Sistema de Informação Hospitalar do SUS (SIH/SUS) em análises de questões relevantes de Saúde Coletiva. Para a busca de artigos publicados em revistas científicas no
Sonia Azevedo Bittencourt   +2 more
doaj  

Development and validation of a deep learning model for predicting postoperative survival of patients with gastric cancer

open access: yesBMC Public Health
Background Deep learning (DL), a specialized form of machine learning (ML), is valuable for forecasting survival in various diseases. Its clinical applicability in real-world patients with gastric cancer (GC) has yet to be extensively validated.
Mengjie Wu   +9 more
doaj   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

The association of serum klotho with pulmonary function among US adults: a cross-sectional study

open access: yesBMC Pulmonary Medicine
Background Klotho has been found to be an anti-aging gene, of which the protein expression level declines with age. Lower levels of klotho protein were found to be associated with a variety of chronic diseases including hypertension, chronic kidney ...
Zichong Long, Huaqiao Mu
doaj   +1 more source

ICD-11 in global public health surveillance: Advancements in infectious disease tracking, non-communicable disease management, and antimicrobial resistance monitoring

open access: yesInformatics and Health
As medical knowledge continues to evolve, the limitations of the International Classification of Diseases, 10th Revision (ICD-10), in supporting public health surveillance and reporting have become increasingly evident.
Yuan Ma   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

Changes in patterns of multimorbidity and associated with medical costs among Chinese middle-aged and older adults from 2013 to 2023: an analysis of repeated cross-sectional surveys in Xiangyang, China

open access: yesFrontiers in Public Health
BackgroundMultimorbidity has become a major public health problem among Chinese middle-aged and older adults, and the most costly to the health care system.
Changyu Ju   +15 more
doaj   +1 more source

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