Results 81 to 90 of about 8,235,207 (290)
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
International Journal of Environmental Research and Public Health, 2018 Medical staff in China’s tertiary public hospitals are responsible for providing healthcare to a considerable number of patients, and their job satisfaction needs attention. The aim of this study is to investigate the job satisfaction of medical staff in
Huixuan Zhou +9 more
semanticscholar +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Hospital survey on patient safety culture in Ethiopian public hospitals: a cross-sectional study
, 2017 BackgroundInternationally, patient safety is increasingly seen as a priority area, and improving patient safety highly depends on achieving a culture that supports and encourages health care staffs to report their errors or near misses without fear of ...
A. Mekonnen +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Quality of Physiotherapy services in Orthopedic wards of private and public sector hospitals
Journal Riphah College of Rehabilitation Sciences, 2021 Objective: The objective of this study was to determine the GAPS (GAP model of service quality is a framework which helps in understanding the customer’s satisfaction.
Shabana Ashraf +6 more
doaj
Pressure injuries in Australian public hospitals: A cost of illness study.
International Journal of Nursing Studies, 2022 S. Nghiem +4 more
semanticscholar +1 more source
Evaluation of Energy Consumption in German Hospitals: Benchmarking in the Public Sector
Energies, 2018 The use of benchmarking in the management of healthcare facilities enables immediate comparison between hospitals. Benchmarking allows ascertaining their expected energy consumption and estimating the possible savings margin.
A. González +2 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo +11 more
wiley +1 more source
BMC Research Notes, 2018 Objective This study aimed at assessing clients’ satisfaction and associated factors among adults. A cross sectional facility based study was conducted on 420 clients of Yekatit 12 Hospital Medical College from 1 June 2016 to 1 July 2016.
Tirhas T. Berehe +3 more
doaj +1 more source