Results 81 to 90 of about 249,594 (250)

Carbohydrate-Based Host-Guest Complexation of Hydrophobic Antibiotics for the Enhancement of Antibacterial Activity

Molecules, 2017
Host-guest complexation with various hydrophobic drugs has been used to enhance the solubility, permeability, and stability of guest drugs. Physical changes in hydrophobic drugs by complexation have been related to corresponding increases in the ...
Daham Jeong, Sang-Woo Joo, Vijay Vilas Shinde, Eunae Cho, Seunho Jung   +4 more
doaj   +1 more source

Coagulative Granular Hydrogels with an Enzyme Catalyzed Fibrin Network for Endogenous Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Coagulative granular hydrogels are composed of packed thrombin‐functionalized microgels that catalyze the conversion of fibrinogen into a secondary fibrin network, filling the interstitial voids. This bio‐inspired approach stabilizes the biomaterial to match the robustness of bulk hydrogels without compromising injectability, mimicking the initial ...
Zhipeng Deng, Camila B. Tovani, Simona Bianco, Gianni Comandini, Aya Elghajiji, Mina Aleemardani, Roxana Moscalu, Jeremie Zappia, Bianca Fernandes, Olivia Annett, Chrissy L. Hammond, Jason Wong, Dave J. Adams, Fabrizio Scarpa, Michael R. Whitehouse, Annela M. Seddon, James P. K. Armstrong   +16 more
wiley   +1 more source

Virtual Machines and Networks - Installation, Performance Study, Advantages and Virtualization Options [PDF]

, 2011
The interest in virtualization has been growing rapidly in the IT industry because of inherent benefits like better resource utilization and ease of system manageability.
Ali, Ishtiaq, Meghanathan, Natarajan
core   +1 more source

Nanotherapies for Atherosclerosis: Targeting, Catalysis, and Energy Transduction

Advanced Healthcare Materials, EarlyView.
Atherosclerosis management is hindered by poor drug targeting and plaque heterogeneity. Nanotechnology overcomes these barriers via three core strategies: (1) target‐engineered nanocarriers that achieve lesion‐specific precision via ligand modification, biomimetic camouflage, stimuli‐responsive release, and self‐propelling nanomotors; (2) catalytic ...
Yuqi Yang, Jingguo Qu, Tonghuan Xiao, Xinyang Han, Michael Tin‐Cheung Ying   +4 more
wiley   +1 more source

Building solids inside nano-space: from confined amorphous through confined solvate to confined ‘metastable’ polymorph [PDF]

, 2015
The nanocrystallisation of complex molecules inside mesoporous hosts and control over the resulting structure is a significant challenge. To date the largest organic molecule crystallised inside the nano-pores is a known pharmaceutical intermediate – ROY
Aceves-Hernandez, Alcoutlabi, Allen, Andronis, Andronis, Andronis, Andronis, Argyo, Babonneau, Beck, Beiner, Borka, Bradley, Carpentier, Charnay, Chen, Crowley, D. E. Braun, Dalal, David, Elmer, Etter, Guilbaud, Ha, Ha, Ha, Haller, Haller, Hamdi, Hamilton, Hamilton, Hamilton, Han, J. Tedder, Jackson, Jackson, Joshi, K. P. Nartowski, Karmwar, Kistenmacher, Kiwilsza, Kolodziejski, L. Fábián, Legendre, Limnell, Lohani, Lu, Lukens, Manzano, Manzano, Markvardsen, Masuda, Nassivera, Otsuka, Otsuka, Rengarajan, Sharma, Son, Stowell, Surwase, Ukmar, Ukmar, Ukmar, Vallet-Regi, Van Speybroeck, Wang, Y. Z. Khimyak, Yoshioka, Zhang, Zhao   +69 more
core   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Controllable ultrahigh-affinity molecular recognition

Supramolecular Materials
High-affinity molecular recognition plays a crucial role in both biological and artificial host-guest systems, ensuring robustness in complex environments or at extremely low concentrations.
Fang-Yuan Chen, Han-Fang Zhang, Kang Cai, Dong-Sheng Guo   +3 more
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Structure of Ni(II) Inclusion Complex in Solid/Solution States and the Enhancement of Catalytic Behavior in Electrochemical Hydrogen Production

Molecules
In this article, we investigate the encapsulation of K2[Ni(maleonitriledithiolate)2] (1) within a host molecule, β-cyclodextrin (β-CD), via single-crystal X-ray analysis.
Tomohiko Hamaguchi, Yuudai Iseki, Ryuta Ishikawa, Akio Mishima, Satoshi Kawata   +4 more
doaj   +1 more source

The effect of host structure on the selectivity and mechanism of supramolecular catalysis of Prins cyclizations. [PDF]

, 2015
The effect of host structure on the selectivity and mechanism of intramolecular Prins reactions is evaluated using K12Ga4L6 tetrahedral catalysts. The host structure was varied by modifying the structure of the chelating moieties and the size of the ...
Bergman, Robert G, Burford, Kristen N, Hart-Cooper, William M, Ozores, Haxel Lionel, Raymond, Kenneth N, Toste, F Dean, Triano, Rebecca M, Yaghoubi, Parastou, Zhao, Chen   +8 more
core   +2 more sources