Pyroptosis maintains immune homeostasis by eliminating damaged or infected cells, but its dysregulation promotes inflammation and cancer progression. The diagram illustrates key activation pathways, links with other programmed cell deaths, and cancer‐specific effects, enhancing its dual protective and pathogenic roles.
Diego Liviu Boaru +18 more
wiley +1 more source
Exploring the lichenization continuum through the marine tripartite symbiosis of Collemopsidium pelvetiae. [PDF]
Pérez-Ortega S +5 more
europepmc +1 more source
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
Oo-No: Ophidiomyces ophidiicola-bacterial interactions and the role of skin lipids in development of ophidiomycosis. [PDF]
Dallas JW +12 more
europepmc +1 more source
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang +16 more
wiley +1 more source
Chemical Signaling and Metabolomic Crosstalk in Endophytic Fungi-Medicinal Plant Symbioses for Natural Product Discovery and Sustainable Bioproduction. [PDF]
Chen Z, Jiang S.
europepmc +1 more source
Plant functional groups and root traits are linked to exudation rates of mature temperate trees
Read the free Plain Language Summary for this article on the Journal blog. Abstract Root exudation affects soil biogeochemistry profoundly, yet it is rarely quantified in mature, field‐grown trees and its controls are poorly understood. We measured rates of carbon (C) exudation in 11 tree species that exhibit divergent root traits, including ...
Young E. Oh +7 more
wiley +1 more source
Protein-biased diets enhance immune responses but increase fungal susceptibility in desert locusts. [PDF]
Tahir SM +5 more
europepmc +1 more source
Horizontal Gene Transfer and Genome Rearrangements Shape Bacterial Adaptation for Bioremediation
Exposure to xenobiotics triggers genome evolution and horizontal gene transfer (HGT), driving the acquisition of novel catabolic functions. These genomic adaptations provide a competitive fitness advantage that reshapes microbial community structure and enhances biodegradation impact.
Zaki Saati‐Santamaría +3 more
wiley +1 more source
Helminth Immune Modulation and Invasive Fungal Infections in Sub-Saharan Africa. [PDF]
Fonte L +3 more
europepmc +1 more source

