Results 41 to 50 of about 17,828 (243)

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

Advanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr, Anne Schmitz, Meshkat Dinarvand, Franziska Wulfert, Sangeetha Shankar, Bjoern F. Hill, Michael Wojak, Juliana Gretz, Marie Britz, Elsa Neubert, Magdalena Shumanska, Sofia Kaushik, Linda Kartaschew, Ivan Bogeski, James Daniel, Sebastian Jung, Johannes Eble, Guido Wabnitz, Luise Erpenbeck, Sebastian Kruss   +19 more
wiley   +1 more source

Echinococcus multilocularis and its intermediate host: a model of parasite-host interplay [PDF]

, 2010
Host-parasite interactions in the E. multilocularis-intermediate host model depend on a subtle balance between cellular immunity, which is responsible for host's resistance towards the metacestode, the larval stage of the parasite, and tolerance ...
Gottstein, Bruno, Vuitton, Dominique Angèle   +1 more
core   +1 more source

A Virus‐Inducible E3–RLCK–MADS Module Coordinates Suppression of Plant Immunity and Fertility in Rice

Advanced Science, EarlyView.
ABSTRACT Viruses often hijack host developmental programs to promote infection, but the mechanistic links between reproductive regulation and antiviral immunity remain incompletely understood. Here, we identify a virus‐triggered hierarchical degradation cascade that links antiviral immunity and fertility regulation in rice. We show that the rice grassy
Yuansheng Wu, Fengling Wu, Shiting Huang, Denglu Yang, Xin Lei, Xue Zhang, Na Liu, Peng Gan, Chuan Li, Jie Zhang, Ming Wu, Qingxiao Jia, Shanshan Zhao, Jianguo Wu   +13 more
wiley   +1 more source

Interplay between viruses and host sumoylation pathways [PDF]

, 2013
Post-translational modification by members of the small ubiquitin-like modifier (SUMO) family of proteins is important for the regulation of many cellular proteins and pathways.
Roger D. Everett, Hale, B.G., Everett, R.D., Boutell, C., Chris Boutell, Benjamin G. Hale   +5 more
core   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

Advanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren, Xiaogang Li, Hao Li, Zenghui Cao, Mengtian Hou, Chunlei Zhao, Nan Lou, Sasa Hu, Yanzhe Li, Qian Ma, Yaoyao Li, Yi Fan, Kunkun Zhao, Kai Zhao, Ding Qiu, Fangping Gong, Zhongfeng Li, Haitao Liu, Xingli Ma, Xingxiang Wang, Dongmei Yin   +20 more
wiley   +1 more source

Bacterial microbiota protect an invasive bark beetle from a pine defensive compound

Microbiome, 2018
Background There is growing evidence that some devastating biotic invasions are facilitated by microbial symbionts. The red turpentine beetle (RTB), an innocuous secondary insect attacking weakened trees in North America, has formed an invasive complex ...
Chihang Cheng, Jacob D Wickham, Li Chen, Dandan Xu, Min Lu, Jianghua Sun   +5 more
doaj   +1 more source

Cx43-mediated hyphal folding counteracts phagosome integrity loss during fungal infection

Microbiology Spectrum, 2023
Phagolysosomes are crucial organelles during the elimination of pathogens by host cells. The maintenance of their membrane integrity is vital during stressful conditions, such as during Candida albicans infection.
Beatriz Cristovao, Lisa Rodrigues, Steve Catarino, Monica Abreu, Teresa Gonçalves, Neuza Domingues, Henrique Girao   +6 more
doaj   +1 more source

Early diabetes‐like phenotypes in germ‐free mice induced by gut microbiota from patients with type 2 diabetes

Animal Models and Experimental Medicine, EarlyView.
Gut microbiota from patients with type 2 diabetes induced early diabetes‐like phenotypes in germ‐free mice, including progressive glucose intolerance and mild renal injury. Longitudinal profiling revealed persistent dysbiosis preceding stable metabolic dysfunction, with coordinated fecal and plasma metabolite alterations and a prominent L‐Dopa ...
Jianghao Feng, Xing Liu, Hua Zhu, Yun Yang, Wei Liu, Xiaoliang Jiang, Zhiwei Yang   +6 more
wiley   +1 more source

Interplay between Candida albicans and the mammalian innate host defense. [PDF]

, 2012
Item does not contain fulltextCandida albicans is both the most common fungal commensal microorganism in healthy individuals and the major fungal pathogen causing high mortality in at-risk populations, especially immunocompromised patients.
Bart-Jan Kullberg, Cheng, S.C., Kullberg, B.J., Mihai G. Netea, Shih-Chin Cheng, Joosten, L.A.B., Netea, M.G., Leo A. B. Joosten   +7 more
core   +1 more source

Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response [PDF]

, 2023
International audienceCandida albicans is a commensal yeast present in the gut of most healthy individuals but with highly variable concentrations. However, little is known about the host factors that influence colonization densities. We investigated how
Zixuan Xie, Marie-Elisabeth Bougnoux, Violaine Saint-André, Darragh Duffy, d'Enfert, Christophe, Delavy, Margot, Dubois, Florian, Margot Delavy, Emmanuelle Le Chatelier, Patin, Etienne, Le Chatelier, Emmanuelle, Duffy, Darragh, Consortium, Milieu Intérieur, Lluis Quintana-Murci, Milieu Intérieur consortium, Alan W. Walker, Etienne Patin, Chaysavanh Manichanh, Xie, Zixuan, Bougnoux, Marie-Elisabeth, Saint-André, Violaine, Quintana-Murci, Lluis, Cole, Nathaniel, Nathaniel Cole, Walker, Alan, Florian Dubois, Sertour, Natacha, Christophe d’Enfert, Manichanh, Chaysavanh, Bougnoux, Marie Elisabeth, Natacha Sertour   +30 more
core   +1 more source