Results 131 to 140 of about 4,950,424 (307)

Interplay of host–pathogen microvesicles and their role in infectious disease

, 2013
The release of extracellular vesicles, whether MVs (microvesicles) or exosomes, from host cells or intracellular pathogens is likely to play a significant role in the infection process.
Lange, S., Ansa-Addo, E.A., Inal, J.M.
core   +1 more source

Mycobacterium bovis infected domestic cats in an officially bovine tuberculosis free country resulting in human infection

One Health
Although the Netherlands is an officially bovine tuberculosis (bTB) free (OTF) country, sporadic infections with Mycobacterium bovis still cause tuberculosis (TB) in (non-bovine) mammals, including humans. We describe for the first time cases of M. bovis
Susanna Commandeur, Marleen van der Most, Jeroen Koomen, Lucien van Keulen, Annemieke Dinkla, Xander Luinenburg, Marieke Escher, Pieter Jacobs, Ingrid Keur, Guy C.M. Grinwis, Erik Weerts, Els M. Broens, Richard Anthony, Miranda Kamst-van Agterveld, Karin Rebel, Erik Huisman, Marloes Heijne, Ad Koets   +17 more
doaj   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Hydrogels Augmented With Artificial Sweeteners can Inhibit Multidrug‐Resistant Acinetobacter baumannii Growth and Biofilm Formation While Demonstrating Safety in Pre‐Clinical Pilot Human Trials

Advanced Healthcare Materials, EarlyView.
Using PVA–borax hydrogels as carriers for off‐the‐shelf artificial sweeteners to fight multidrug‐resistant A. baumannii. These soft, biocompatible hydrogels rapidly reduce bacterial viability within multidrug‐resistant A. baumannii biofilms by more than 99% within one hour and sustain antimicrobial activity over time, while demonstrating safety in both
Jie Han, Mohamed Soliman, Bin Zhang, Dominika Krawiel, Ronan R. McCarthy   +4 more
wiley   +1 more source

A nutritive view on the host-pathogen interplay.

, 2005
The interaction between pathogenic microbes and their host is determined by survival strategies on both sides, including competition for essential nutrients.
Kaufmann, Stefan HE, Schaible, Ulrich E, Kaufmann, Stefan H. E., Schaible, Ulrich E.   +3 more
core   +1 more source

Vector-pathogen-Host Machine Learning and Data Mining Review Data

, 2020
DM & ML application in Host-Vector-Pathogen relationship ...
Etienne Gnimpieba (4808223)
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Deciphering the viral landscape in gastric cancer: comprehensive characterization and identification of the gastric cancer virome

mBio
Infectious diseases caused by pathogenic microorganisms and tumors arising from uncontrolled cell proliferation can be intricately linked through the lens of viromics.
Dan Xiang, Shaoying Li, Jiayi Zuo, Chenchen Mao, Yangxuan Lin, Cong Long, Pingping Cai, Weiwei Liu, Xiaorong Lu, Miaofang Xiao, Wangkai Xie, Chenbin Chen, Dianfeng Mei, Kezhi Lin, Zheng Han, Xian Shen, Xiangyang Xue, Shurong Shen   +17 more
doaj   +1 more source

Advancing Human Skin Equivalents: The Crucial Role of Neurovascular Integration

Advanced Healthcare Materials, EarlyView.
This review discusses the importance of integrating vascular and peripheral nerve systems into human skin equivalents (HSEs) to better recapitulate native skin physiology. Recent advances in vascularized, innervated, and neurovascularized HSEs are highlighted, together with emerging bioengineering strategies, current challenges, and future ...
Hao Wu, Lorenzo Moroni, Nicolas Lebonvallet, Vincent Flacher, Paul Wieringa   +4 more
wiley   +1 more source