Results 141 to 150 of about 803,197 (352)

Generating Cell Surface Nucleated Hydrogels with an Artificial Membrane‐Binding Transglutaminase

Advanced Functional Materials, EarlyView.
Cell‐based therapies require advanced strategies to enhance cell delivery and bioactivity. Cell membrane engineering offers an avenue to impart new functions to delivered cells to boost their viability and function. Here, an artificial membrane‐binding transglutaminase is generated and biophysically characterized.
Rosalia Cuahtecontzi Delint, Tao Li, Kapil D. Patel, Will H. Zhang, Ben M. Carter, Graham J. Day, Adam W. Perriman   +6 more
wiley   +1 more source

Uncovering biomarkers for chronic toxoplasmosis detection highlights alternative pathways shaping parasite dormancy

EMBO Molecular Medicine
Toxoplasma gondii, a neurotropic protozoan, causes toxoplasmosis, a prevalent zoonotic and food-borne infection, posing significant risks to immunocompromised individuals and congenital cases.
Marie G Robert, Christopher Swale, Belen Pachano, Léa Dépéry, Valeria Bellini, Céline Dard, Dominique Cannella, Charlotte Corrao, Lucid Belmudes, Yohann Couté, Alexandre Bougdour, Hervé Pelloux, Emmanuelle Chapey, Martine Wallon, Marie-Pierre Brenier-Pinchart, Mohamed-Ali Hakimi   +15 more
doaj   +1 more source

SURVEILLANCE OF β-LACTAMASE GENES OF SALMONELLA FROM CHICKEN IN WET MARKETS OF METRO MANILA, PHILIPPINES

Biotropia: The Southeast Asian Journal of Tropical Biology
Article Highlights - blaCTX-M gene in 24.7% while blaTEM gene in 11.2% of Salmonella isolates. - Coexistence of blaCTX-M groups II and IV in all blaCTX-M-positive isolates.
Miles Madayag, Rance Derrick Pavon, Jonah Feliza Mora, Khristine Balaga, Windell Rivera   +4 more
doaj   +1 more source

Microneedle‐Based Biofertilizer Delivery Improves Plant Growth Through Microbiome Engineering

Advanced Functional Materials, EarlyView.
This figure shows how microneedles are used to deliver biofertilizers to enhance plant growth through microbial migration, metabolic reprogramming, and changes in plant endogenous microbiome. Abstract This study presents a microneedle‐based system for the delivery of rhizospheric biofertilizers into plant tissues to enhance growth.
Zhicheng Le, Sevugan Mayalagu, Cheng‐Yen Chen, Raktim Bhattacharya, Abhishek Gupta, Jingyuan Li, Zhi Wei Norman Teo, Yufeng Shou, Arya Gopinath MP, Danni Zhong, Tedrick Thomas Salim Lew, Hao Yu, Naweed I. Naqvi, Sanjay Swarup, Andy Tay   +14 more
wiley   +1 more source

Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells

Infection and Immunity, 2019
Many intracellular bacteria, including the obligate intracellular pathogen Chlamydia trachomatis, grow within a membrane-bound bacterium-containing vacuole (BCV).
M. Olson, Ray E. Widner, Lisa M. Jorgenson, A. Lawrence, Dragana Lagundžin, Nicholas T. Woods, S. Ouellette, E. A. Rucks   +7 more
semanticscholar   +1 more source

Injectable Dual‐Network Hydrogel System for Osteochondral Repair Combining Immunomodulation, Mechanical Adaptability, and Enhanced Tissue Integration

Advanced Functional Materials, EarlyView.
A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui, Feifei Zhou, Yuan Luo, Tao Ouyang, Huiwu Zhang, Songmiao Cheng, Qiang Li, Xu Jiang, Yingying Yu, Yicheng Wang, Hong Ming   +10 more
wiley   +1 more source

Serpin functions in host-pathogen interactions

PeerJ, 2018
Serpins are a broadly distributed superfamily of protease inhibitors that are present in all kingdoms of life. The acronym, serpin, is derived from their function as potent serine proteases inhibitors.
J. Bao, G. Pan, M. Poncz, Junhong Wei, Maoshuang Ran, Zeyang Zhou   +5 more
semanticscholar   +1 more source

Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents

Advanced Functional Materials, EarlyView.
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras, Imelda Raczkiewicz, Peggy Bouquet, Jean‐Philippe Dacquin, Jeremy Dhainaut, Anne Goffard, Christophe Volkringer   +6 more
wiley   +1 more source

Dual‐Layer Living Hydrogel Enables On‐Demand Delivery of Phages and Probiotics for Synergistic Wound Infection Therapy

Advanced Functional Materials, EarlyView.
A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao, Darine D'Adam, Anna Hu, Sixuan Zhang, Josua Roduner, Katharina Maniura‐Weber, Qun Ren   +6 more
wiley   +1 more source

Integrated pathogen load and dual transcriptome analysis of systemic host-pathogen interactions in severe malaria

Science Translational Medicine, 2017
Host and parasite RNA sequencing is combined with parasite load estimates to reveal mechanisms associated with human severe malaria. Uncomplicating malaria Plasmodium falciparum infections can progress to severe malaria, resulting in organ failure and ...
Hyun Jae Lee, Athina Georgiadou, M. Walther, D. Nwakanma, L. Stewart, M. Levin, T. Otto, D. Conway, L. Coin, A. Cunnington   +9 more
semanticscholar   +1 more source