Results 271 to 280 of about 803,197 (352)

EXTRACELLULAR VESICLES AS NOVEL INDICATORS OF GUT DYNAMICS AND HOST-PATHOGEN INTERACTIONS IN GASTROINTESTINAL INFECTIONS

Premathilaka, Chanaka
openalex   +1 more source

MGM as a Large‐Scale Pretrained Foundation Model for Microbiome Analyses in Diverse Contexts

Advanced Science, EarlyView.
We present the Microbial General Model (MGM), a transformer‐based foundation model pretrained on over 260,000 microbiome samples. MGM learns contextualized microbial representations via self‐supervised language modeling, enabling robust transfer learning, cross‐regional generalization, keystone taxa discovery, and prompt‐guided generation of realistic,
Haohong Zhang, Yuli Zhang, Zixin Kang, Jiayun Xiong, Ronghua Yang, Kang Ning   +5 more
wiley   +1 more source

Phytoplasmas: Molecular Characterization and Host-Pathogen Interactions. [PDF]

Biology (Basel)
Wei W, Zhao Y, Quaglino F.
europepmc   +1 more source

Conservationof Putative Liquid–Liquid PhaseSeparating Proteins in Multiple Drug-Resistant Mycobacteriumtuberculosis: Role in Host–Pathogen Interactions?

Jasdeep Singh (596413), Prashant Pradhan (11262036), Arti Kataria (18581878), Sanjeev Sinha (454603), Nasreen Z. Ehtesham (251048), Peter N. Monk (680791), Seyed E. Hasnain (10226759)   +6 more
openalex   +1 more source

Host–pathogen interactions in Streptococcus pyogenes infections, with special reference to puerperal fever and a comment on vaccine development

, 2004
Thomas Areschoug, Fredric Carlsson, Margaretha Stålhammar‐Carlemalm, Gunnar Lindahl   +3 more
openalex   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Enigmatic roles of <i>Vibrio cholerae</i> hemolysin/cytolysin in the bacterial pathogenesis and host-pathogen interactions. [PDF]

J Bacteriol
Singh M, Puravankara S, Mukhopadhaya A, Chattopadhyay K.   +3 more
europepmc   +1 more source

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

Emerging insights into the type I secretion system: a key player in <i>Salmonella</i> virulence and host-pathogen interactions. [PDF]

mBio
Li S, Liu H, Qiu J.
europepmc   +1 more source

The Collaborative Cross: A Systems Genetics Resource for Studying Host-Pathogen Interactions

Cell Host and Microbe, 2019
Kelsey E. Noll, M. Ferris, M. Heise
semanticscholar   +1 more source