Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
High water availability increases the negative impact of a native hemiparasite on its non-native host [PDF]
, 2016 Environmental factors alter the impacts of parasitic plants on their hosts. However, there have been no controlled studies on how water availability modulates stem hemiparasites' effects on hosts.
Facelli, JM +8 more
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Population-related variation in plant defense more strongly affects survival of an herbivore than its solitary parasitoid wasp [PDF]
, 2011 The performance of natural enemies, such as parasitoid wasps, is affected by differences in the quality of the host’s diet, frequently mediated by species or population-related differences in plant allelochemistry. Here, we compared survival, development
Jeffrey A. Harvey +3 more
core +1 more source
Fungal Small RNAs Suppress Plant Immunity by Hijacking Host RNA Interference Pathways
Science, 2013 RNA on the Attack Plant microbial pathogens often work through protein effectors that are delivered into the plant cells to disrupt critical cellular functions. Weiberg et al. (p.
Arne Weiberg +7 more
semanticscholar +1 more source
Host selection shapes crop microbiome assembly and network complexity.
New Phytologist, 2020 Plant microbiomes are essential to host health and productivity but the ecological processes that govern crop microbiome assembly are not fully known. Here we examined bacterial communities across 684 samples from soils (rhizosphere and bulk soil) and ...
C. Xiong +11 more
semanticscholar +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Host location in a specialist parasitoid wasp via olfactory cues – a physiological, behavioural and morphological study [PDF]
, 2012 For successful host location, parasitoids are thought to have evolved different strategies to filter relevant olfactory cues which indicate the presence of the host. Because of their versatility in their ecology and behaviour, as well as their fine tuned
Groll, Helga
core
Are insect frugivores always plant pests? The impact of fruit fly (Diptera: Tephritidae) larvae on host plant fitness [PDF]
, 2012 Herbivory is generally regarded as negatively impacting on host plant fitness. Frugivorous insects, which feed directly on plant reproductive tissues, are predicted to be particularly damaging to hosts.
Wilson, Alexsis J. +3 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source