Results 111 to 120 of about 3,781,937 (305)

The transcriptome of Nacobbus aberrans reveals insights into the evolution of sedentary endoparasitism in plant-parasitic nematodes [PDF]

, 2014
This work was supported by the Biotechnology and Biological Sciences Research Council and The James Hutton Institute (JHI). The James Hutton Institute receives funding from the Scottish Government.
Jones, John T., Cock, Peter J. A., Urwin, P.E., Eves-van den Akker, Sebastian, Cock, P.J.A., Danchin, Etienne, Danchin, Etienne G. J., Lilley, Catherine J., Urwin, Peter E., Jones, J.T., Lilley, C.J., Eves-van den Akker, S, Rancurel, Corinne   +12 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Modulation of host immunity by beneficial microbes [PDF]

, 2012
In nature, plants abundantly form beneficial associations with soilborne microbes that are important for plant survival and, as such, affect plant biodiversity and ecosystem functioning.
Pieterse, C.M.J., Zamioudis, C, Sub Plant-Microbe Interactions, Corné M. J. Pieterse, Christos Zamioudis, Plant Microbe Interactions   +5 more
core   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Extreme host plant conservatism during at least 20 million years of host plant pursuit by oak gallwasps

, 2009
Diversification of insect herbivores is often associated with coevolution between plant toxins and insect countermeasures, resulting in a specificity that restricts host plant shifts.
Cook, James M., Nicholls, James A., Melika, George, Stone, Graham N., Di Pierro, Erica, Hernandez-Lopez, Antonio, Pujade-Villar, Juli, Melika, G., di Pierro, E., Hernandez-Lopez, A., Cook, J. M., Pujade-Villar, J., Nicholls, J. A., Stone, G. N.   +13 more
core   +1 more source

Olfactory responses of Dasineura Dielsi Rübsaamen (Diptera: Cecidomyiidae) females to host plant volatiles [PDF]

, 2012
Includes abstract.Includes bibliographical references.In 2001, Dasineura dielsi (Diptera: Cecidomyiidae), a gall midge, was introduced into South Africa as a biological control agent on the invasive alien plant species, Acacia cyclops (Mimosaceae).
Kotze, MJ
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Host Plant Resistance to Insects in Vegetable Crops

Host plant resistance is an effective approach to manage insect pests in vegetable crops. This approach involves the use of plant traits that deter or reduce insect feeding and reproduction involving the mechanisms of antibiosis, antixenosis, and ...
Kumaraswamy, Sunil, Nasif, Saifullah Omar, Siddique, Abu Bakar, Chowdary, Rajesh, Chaitanya, Alamuru Krishna, Karuppannasamy, Ashok, Mohan, Muthugounder   +6 more
core   +1 more source