Results 51 to 60 of about 674,293 (317)

Host sexual dimorphism and parasite adaptation [PDF]

, 2012
In species with separate sexes, parasite prevalence and disease expression is often different between males and females. This effect has mainly been attributed to sex differences in host traits, such as immune response.
Duneau, D., Ebert, Dieter, Dieter Ebert, David Duneau, Duneau David, Ebert Dieter   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Genomic and Epidemiological Evidence of a Dominant Panton-Valentine Leucocidin-Positive Methicillin Resistant Staphylococcus aureus Lineage in Sri Lanka and Presence Among Isolates From the United Kingdom and Australia

Frontiers in Cellular and Infection Microbiology, 2019
Objective: To undertake the first detailed genomic analysis of methicillin-resistant Staphylococcus aureus (MRSA) isolated in Sri Lanka.Methods: A prospective observational study was performed on 94 MRSA isolates collected over a 4 months period from the
Sharla M. McTavish, Sarah J. Snow, Ellie C. Cook, Bruno Pichon, Sarah Coleman, Geoffrey W. Coombs, Stanley Pang, Cesar A. Arias, Cesar A. Arias, Cesar A. Arias, Lorena Díaz, Lorena Díaz, Emma Boldock, Emma Boldock, Steve Davies, Mangala Udukala, Angela Marie Kearns, Sisira Siribaddana, Sisira Siribaddana, Thushan I. de Silva, Thushan I. de Silva   +20 more
doaj   +1 more source

Allelic Variation in Protein Tyrosine Phosphatase Receptor Type-C in Cattle Influences Erythrocyte, Leukocyte and Humoral Responses to Infestation With the Cattle Tick Rhipicephalus australis

Frontiers in Immunology, 2021
The protein tyrosine phosphatase receptor type-C (PTPRC) gene encodes the common leukocyte antigen (CD45) receptor. CD45 affects cell adhesion, migration, cytokine signalling, cell development, and activation state.
Nicholas N. Jonsson, David K. Cox, Emily K. Piper, Emily F. Mantilla Valdivieso, Constantin Constantinoiu, Louise A. Jackson, Michael J. Stear, Elizabeth M. Ross, Ala E. Tabor   +8 more
doaj   +1 more source

Phenotypic analysis of host-parasite interactions in lambs infected with Teladorsagia circumcincta

, 2008
Female Blackface lambs expected to exhibit genetic variability for resistance to gastrointestinal nematodes, were either exposed to continuous experimental infections of Teladorsagia circumcincta or were sham-dosed to monitor phenotypic responses to ...
Beraldi, D., Hopkins, J., J. Hopkins, Bishop, S. C., D. Beraldi, Pemberton, J. M., S.C. Bishop, B.H. Craig, J.M. Pemberton, Craig, B. H.   +9 more
core   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Approaches to assessing host resistance. [PDF]

Environmental Health Perspectives, 1982
There is increasing evidence that chronic, subclinical exposure to certain environmental pollutants may upset immune responsiveness and alter susceptibility of animals to infectious agents. Environmental chemicals or drugs may affect diverse aspects of the immune system, leading to immunosuppression, immunopotentiation, hypersensitivity or perturbed ...
S G, Bradley, P S, Morahan
openaire   +2 more sources

Mcl-1 is a key regulator of apoptosis resistance in Chlamydia trachomatis-infected cells

, 2008
Chlamydia are obligate intracellular bacteria that cause variety of human diseases. Host cells infected with Chlamydia are protected against many different apoptotic stimuli.
Manu Sharma, Christopher J Froelich, Oswald Monique, Sharma Manu, Lohmann, C., Oswald, M., Christine Lohmann, Sharma, Manu, Thomas Rudel, Froelich, C., Sharma, M., Monique Oswald, Froelich, Christopher J., Oliver Thieck, Rajalingam, Krishnaraj, Rudel Thomas, Thieck Oliver, Thieck, Oliver, Oswald, Monique, Froelich Christopher J., Rajalingam, K., Lohmann Christine, Rudel, T., Thieck, O., Rudel, Thomas, Krishnaraj Rajalingam, Rajalingam Krishnaraj, Lohmann, Christine   +27 more
core   +1 more source

Resolving the infection process reveals striking differences in the contribution of environment, genetics and phylogeny to host-parasite interactions [PDF]

, 2011
Background Infection processes consist of a sequence of steps, each critical for the interaction between host and parasite. Studies of host-parasite interactions rarely take into account the fact that different steps might be influenced by different ...
Ebert, Dieter, Dieter Ebert, Ben-Ami, Frida, Laforsch Christian, Duneau David, Ebert Dieter, David Duneau, Laforsch, C., Luijckx Pepijn, Duneau, David, Luijckx, P., Ben-Ami, F., Luijckx, Pepijn, Frida Ben-Ami, Pepijn Luijckx, Duneau, D., Ben-Ami Frida, Christian Laforsch, Laforsch, Christian   +18 more
core   +1 more source