Results 1 to 10 of about 7,506 (214)

Host genetic susceptibility to mycetoma. [PDF]

PLoS Neglected Tropical Diseases, 2020
Mycetoma is one of the badly neglected tropical diseases, characterised by subcutaneous painless swelling, multiple sinuses, and discharge containing aggregates of the infecting organism known as grains. Risk factors conferring susceptibility to mycetoma
Rayan S Ali, Melanie J Newport, Sahar Mubarak Bakhiet, Muntaser E Ibrahim, Ahmed Hassan Fahal   +4 more
doaj   +4 more sources

Vertebrate Host Susceptibility to Heartland Virus [PDF]

Emerging Infectious Diseases, 2016
Heartland virus (HRTV) is a recently described phlebovirus initially isolated in 2009 from 2 humans who had leukopenia and thrombocytopenia. Serologic assessment of domestic and wild animal populations near the residence of 1 of these persons showed high
Angela M. Bosco-Lauth, Amanda E. Calvert, J. Jeffrey Root, Tom Gidlewski, Brian H. Bird, Richard A. Bowen, Atis Muehlenbachs, Sherif Zaki, Aaron C. Brault   +8 more
doaj   +3 more sources

Polymorphisms in Processing and Antigen Presentation-Related Genes and Their Association with Host Susceptibility to Influenza A/H1N1 2009 Pandemic in a Mexican Mestizo Population

Viruses, 2020
(1) Background: The influenza A/H1N1 pdm09 virus rapidly spread throughout the world. Despite the inflammatory and virus-degradation pathways described in the pathogenesis of influenza A virus (IAV) infection, little is known about the role of the single
Marco Antonio Ponce-Gallegos, Aseneth Ruiz-Celis, Enrique Ambrocio-Ortiz, Gloria Pérez-Rubio, Alejandra Ramírez-Venegas, Nora E. Bautista-Félix, Ramcés Falfán-Valencia   +6 more
doaj   +3 more sources

Attenuate host susceptibility to respiratory virus invasion by inhibiting interactions between host proteins SLC16A3 and AP1G1

Microbiology Spectrum
Modulating cell endocytosis activity to reduce host susceptibility to virus represents a promising strategy for antiviral drug development. In this study, we reveal that lactate transporter SLC16A3 is a critical host factor for reducing diverse virus ...
Xinqi Deng, Rongge He, Jingsheng Zhang, Qingling Rao, Heng Chen, Zhixing Huang, ZiYi Hu, Shan Cao, Ziyu Wang, Shanshan Guo, Chunguo Wang, Xiaolan Cui   +11 more
doaj   +3 more sources

Host Genetics of Tuberculosis Susceptibility

McGill Journal of Medicine, 2020
N ...
Tania Di Pietrantonio, Caroline Gallant, Erwin Schurr   +2 more
doaj   +3 more sources

Nlrp3 Increases the Host’s Susceptibility to Tularemia [PDF]

Frontiers in Microbiology, 2021
Francisella tularensis(F. tularensis) is a Gram-negative, intracellular bacterium and the causative agent of a fatal human disease known as tularemia. The CDC has classifiedF. tularensisas a Tier 1 Category A select agent based on its ease of aerosolization, low infectious dose, past use as a bioweapon, and the potential to be used as a bioterror agent.
Ragavan V. Suresh, Elizabeth W. Bradley, Matthew Higgs, Vincenzo C. Russo, Maha Alqahtani, Wiehua Huang, Chandra Shekhar Bakshi, Meenakshi Malik   +7 more
openaire   +3 more sources

Intestinal shedding of enteric agents in histo-blood group antigen-secretor children in an Australian community-based birth cohort study

Journal of Pediatric and Neonatal Individualized Medicine, 2022
Histo-blood group antigens are inherited polymorphic glycans expressed on mucosal epithelial cell surfaces and shed in secretions. They act as receptors for gastrointestinal pathogens. Those expressing these antigens are categorized as secretors and have
Gabor Mihala, Robert S. Ware, Catherine Cheung, Stephen B. Lambert, Peter D. Sly, David M. Whiley, Keith Grimwood   +6 more
doaj   +1 more source

Tuberculosis Infectiousness and Host Susceptibility [PDF]

The Journal of Infectious Diseases, 2017
The transmission of tuberculosis is complex. Necessary factors include a source case with respiratory disease that has developed sufficiently for Mycobacterium tuberculosis to be present in the airways. Viable bacilli must then be released as an aerosol via the respiratory tract of the source case.
Turner, RD, Chiu, C, Churchyard, GJ, Esmail, H, Lewinsohn, DM, Gandhi, NR, Fennelly, KP   +6 more
openaire   +3 more sources

ML-AdVInfect: A Machine-Learning Based Adenoviral Infection Predictor

Frontiers in Molecular Biosciences, 2021
Adenoviruses (AdVs) constitute a diverse family with many pathogenic types that infect a broad range of hosts. Understanding the pathogenesis of adenoviral infections is not only clinically relevant but also important to elucidate the potential use of ...
Onur Can Karabulut, Betül Asiye Karpuzcu, Erdem Türk, Ahmad Hassan Ibrahim, Barış Ethem Süzek, Barış Ethem Süzek   +5 more
doaj   +1 more source

What Is a Host? Attributes of Individual Susceptibility [PDF]

Infection and Immunity, 2018
ABSTRACTIn every epidemic some individuals become sick and some may die, whereas others recover from illness and still others show no signs or symptoms of disease. These differences highlight a fundamental question of microbial pathogenesis: why are some individuals susceptible to infectious diseases while others who acquire the same microbe remain ...
Arturo Casadevall, Liise-anne Pirofski
openaire   +2 more sources