Results 81 to 90 of about 434,696 (303)
A STRANGER: PROJECTION OF ALIENATED FEMALE INDIVIDUALITY IN JEAN RHYS’S SHORT STORIES
Іноземна філологіяThe present study examines the prose texts written by Jean Rhys (1890–1979), a British woman writer of modernist literature. It is based on the perusal of several short stories, among others: “In the Rue de l’Arrivée”, “A Night”, “La Grosse Fifi ...
Nadiya Polishchuk
doaj +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Dynamics of partisan journalism: journalist-source relations in the context of a local newspaper's anti-paedophile housing agenda [PDF]
, 2006 This article explores the influence of partisanship on the framing of a local news agenda. Using a case study approach, it explores how one local newspaper in the East Midlands of England, the Nottingham-based Evening Post, reacted with hostility to ...
Cross, S, Lockyer, S
core
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Experience of anger in psychological and works of fathers of the church
Консультативная психология и психотерапия, 2011 This paper discusses the scientific understanding of the experience of anger by psychologists and fathers of the Church. The author demonstrates a fundamental difference between the two approaches, including the purposes of exploring anger.
Gavrilova T.P.
doaj
Moralization and the 2012 U.S. Presidential Election Campaign
Journal of Social and Political Psychology, 2015 People vary in the extent to which they imbue an attitude with moral conviction; however, little is known about what makes an issue transform from a relatively non-moral preference to a moral conviction. In the context of the 2012 U.S.
Mark J. Brandt +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Nordic Journal of Migration Research, 2015 This study analyses the changing role of the family as a source of social capital in aiding migration, settlement and social integration of Zimbabwean migrants.
Chipo Hungwe
doaj +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Molecular Oncology, EarlyView.Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source