Results 241 to 250 of about 30,308 (277)

Formulation Development of Solid Self-Nanoemulsifying Drug Delivery Systems of Quetiapine Fumarate via Hot-Melt Extrusion Technology: Optimization Using Central Composite Design. [PDF]

Pharmaceutics
Uttreja P, Youssef AAA, Karnik I, Sanil K, Narala N, Wang H, Elkanayati RM, Vemula SK, Repka MA.   +8 more
europepmc   +1 more source

Mechanical Characterization of Additively Manufactured Poly(3‐hydroxybutyrate‐co‐3‐hydroxyhexanoate) Biopolymer

Journal of Applied Polymer Science, Volume 143, Issue 9, March 5, 2026.
Thermal behavior, specimen fabrication, and mechanical benchmarking of PHBH produced by additive manufacturing and injection molding. ABSTRACT Poly(3‐hydroxybutyrate‐co‐3‐hydroxyhexanoate) (PHBH) is a biodegradable polyester with strong potential for marine and packaging applications common for thermoplastic polymers, yet its performance after being ...
Lorenzo De Noni, Sara West, Hudson Legendre, Hung‐Jue Sue, Albert E. Patterson   +4 more
wiley   +1 more source

Entropy Generation Analysis due to Permeable Exponential Stretching in Boundary Layer Flows

Heat Transfer, Volume 55, Issue 2, Page 781-796, March 2026.
ABSTRACT Entropy generation represents the irreversible loss of useful energy in thermal–fluid systems, directly reducing efficiency in applications, such as microelectronics cooling, nanofluid‐based heat exchangers, and polymer processing. This study investigates entropy generation in a two‐phase viscoelastic nanofluid flow over a permeable ...
Khodani Sherrif Tshivhi, Maashutha Samuel Tshehla   +1 more
wiley   +1 more source

Hot-melt extrusion with poorly soluble drugs

, 2008
openaire   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Hot Melt Extrusion: A Paradigm–Changing Technology

Recent Advances in Drug Delivery and Formulation, 2023
Abstract: Over the last few decades, hot melt extrusion (HME) has found extensive adaptability and utility as a viable drug delivery option in the pharmaceutical industry. HME has already been validated as a robust, novel technique mainly used for the correction of solubility and bioavailability of poorly soluble drugs.
Vaibhav G. Bhamare, Ravindra K. Kamble
openaire   +2 more sources

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

Drug Development and Industrial Pharmacy, 2016
The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by the use of amorphous solid dispersions. Phase diagrams of ABZ-polymer binary mixtures generated from Flory-Huggins theory were used to assess miscibility and processability.
Soraya, Hengsawas Surasarang, Justin M, Keen, Siyuan, Huang, Feng, Zhang, James W, McGinity, Robert O, Williams   +5 more
openaire   +2 more sources

Hot-Melt Extrusion: a Roadmap for Product Development

AAPS PharmSciTech, 2021
Hot-melt extrusion has found extensive application as a feasible pharmaceutical technological option over recent years. HME applications include solubility enhancement, taste masking, and sustained drug release. As bioavailability enhancement is a hot topic of today's science, one of the main applications of HME is centered on amorphous solid ...
Marta F, Simões, Rui M A, Pinto, Sérgio, Simões   +2 more
openaire   +2 more sources

Continuous Processing of Micropellets via Hot-Melt Extrusion

AAPS PharmSciTech, 2022
Microparticulate drug delivery systems, e.g., micropellets (MPs), are used in a variety of pharmaceutical formulations such as suspensions, injectable systems, and capsules. MPs are currently manufactured mainly via batch, solvent-based processes, e.g., spray-drying and solvent evaporation-extraction.
Martin Spoerk, Ioannis Koutsamanis, Andreas Kottlan, Christian Makert, Michael Piller, Manuel Rajkovaca, Amrit Paudel, Johannes Khinast   +7 more
openaire   +2 more sources