Results 281 to 290 of about 1,076,798 (336)
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Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti, 2012
Hot-melt extrusion (HME), originally coming from plastic industry, becomes at present an interesting technology also in the pharmaceutical field. The number of drugs with poor solubility and also bioavailability is increasing. In addition, most of the organic drugs are exhibiting polymorphism.
Salandová, Jana, Rabišková, Miloslava
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Hot-melt extrusion (HME), originally coming from plastic industry, becomes at present an interesting technology also in the pharmaceutical field. The number of drugs with poor solubility and also bioavailability is increasing. In addition, most of the organic drugs are exhibiting polymorphism.
Salandová, Jana, Rabišková, Miloslava
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Hot-melt extrusion of sugar-starch-pellets
International Journal of Pharmaceutics, 2015Sugar-starch-pellets (syn. sugar spheres) are usually manufactured through fluidized bed granulation or wet extrusion techniques. This paper introduces hot-melt extrusion (HME) as an alternative method to manufacture sugar-starch-pellets. A twin-screw extruder coupled with a Leistritz Micro Pelletizer (LMP) cutting machine was utilized for the ...
Chi-Wah, Yeung, Hubert, Rein
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Hot-melt Extrusion Technology and Pharmaceutical Application
Therapeutic Delivery, 2012The use of hot-melt extrusion (HME) within the pharmaceutical industry is steadily increasing, due to its proven ability to efficiently manufacture novel products. The process has been utilized readily in the plastics industry for over a century and has been used to manufacture medical devices for several decades.
Wilson, M. +3 more
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Pharmaceutical Applications of Hot-Melt Extrusion: Part II
Drug Development and Industrial Pharmacy, 2007Interest in hot-melt extrusion techniques for pharmaceutical applications is growing rapidly with well over 100 papers published in the pharmaceutical scientific literature in the last 12 years. Hot-melt extrusion (HME) has been a widely applied technique in the plastics industry and has been demonstrated recently to be a viable method to prepare ...
Michael A, Repka +7 more
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Hot Extrusion of Aluminum Chips
2012The process of hot extrusion is a promising approach for the direct recycling of aluminum machining chips to aluminum profiles. The presented technology is capable of saving energy, as remelting of aluminum chips can be avoided. Depending on the deformation route and process parameters, the chip-based aluminum extradates showed mechanical properties ...
A. Erman Tekkaya +3 more
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Hot Hydrostatic Extrusion of Steel
1980Three kinds of steel, 0.40% carbon steel, Cr-Mo case hardening steel and 304 stainless steel, are hydrostatically extruded at high temperatures up to 1300°C.
M. Nishihara +4 more
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Study on hot extrusion of tubes
Journal of Materials Processing Technology, 1997Abstract In this study, a numerical simulation model for forward hot extrusion processes of tube is developed by combining the upper bound method with the finite difference method. It is proposed to predict the deformation behaviors and forming load during the extrusion process.
Hsiang, S. H., Liao, C. S.
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Fusion Engineering and Design, 2015
Abstract Be–30.8 wt.%Ti powder mixture was extruded in copper and steel containers at 700 and 900 °C, respectively. In both cases, achieved extrusion ratio was 7:1. Investigations of microstructure of manufactured Be–Ti rods revealed that processing temperature has a great influence on the metal flow during the extrusion as well as formation of ...
Kurinskiy, P. +3 more
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Abstract Be–30.8 wt.%Ti powder mixture was extruded in copper and steel containers at 700 and 900 °C, respectively. In both cases, achieved extrusion ratio was 7:1. Investigations of microstructure of manufactured Be–Ti rods revealed that processing temperature has a great influence on the metal flow during the extrusion as well as formation of ...
Kurinskiy, P. +3 more
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Hot Hydrostatic Extrusion Process
1985Hydrostatic extrusion was proposed as a new lubricated extrusion process about 20 years ago, although the idea was patented by J. Robertson in 1893. From that time on, the process has been applied to composite materials, special alloys, and exotic or precious metals, with the results of diverse research and development indicating its eventual ...
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Preliminary evaluation of hot extrusion miniaturization
Journal of Materials Science, 1999Experiments were conducted to examine the feasibility of hot extruding metals on a miniature scale thus providing a quick and cheap method of studying extrusion in general. Aluminium was successfully extruded using a new miniature hot extrusion rig, producing aluminium wires (maximum diameter 2.6 mm) as opposed to rods.
K. Morsi +3 more
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