Results 41 to 50 of about 8,192,878 (290)

The Influence of Non-Nociceptive Factors on Hot-Plate Latency in Rats

, 2010
The hot plate is a widely used test to assess nociception. The effect of non-nociceptive factors (weight, sex, activity, habituation, and repeated testing) on hot-plate latency was examined.
Weber, Ceri, Michael M. Morgan, Bobeck, Erin N., Bobeck, Erin N, Morgan, Michael M., Amanda Gunn, Erin N. Bobeck, Ceri Weber, Gunn, Amanda, Morgan, Michael M   +9 more
core   +1 more source

Change from baseline as an outcome illustrates escape behaviour of rats in hot plate method [PDF]

, 2017
Background: The Hot Plate test is a thermal hyperalgesia model to assess the analgesic activity of many compounds. Traditional analysis compares reaction times with controls, reports only analgesic activity without considering escape reflex.
Rajesh Kumar, Manchi, Rama Mohan Pathapati, Madhavulu Buchineni, Manchi Rajesh Kumar, Kudagi, B. L., Pathapati, Rama Mohan, Buchineni, Madhavulu, B. L. Kudagi   +7 more
core   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Biodiesel deposit characterization on hot chamber test rig with biodiesel fuels (B20) and bioaditif essential oil (atsiri)

E3S Web of Conferences, 2018
In this study, the deposit formation of B20-NA biodiesel with the addition of bioadditive Essential Oil with different variations, B20 + Essential Oil 1:2000, B20 + Essential Oil 1:3000, B20 + Essential Oil 1: 4000 and B20 + Essential Oil 1:5000 method ...
Suryantoro Muchammad Taufiq, Sugiarto Bambang, Setiapraja Hari, Yubaidah Siti, Mulyono Ary Budi, Attharik Mochammad Ilham, Ariestiawan Muhamad Raihan, Cohen Andro   +7 more
doaj   +1 more source

Design, Synthesis and Biological Activity Evaluation of Arylpiperazine Derivatives for the Treatment of Neuropathic Pain

Molecules, 2011
In this work, a series of arylpiperazine derivatives were synthesized and screened by in vivo pharmacological trials. Among the tested compounds, 2-(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)-1-phenylethanone (18) and 2-(4-(2,3-dimethylphenyl)piperazin-
Guisen Zhang, Jianqi Li, Bi-Feng Liu, Xiangqing Xu, Guan Wang, Yin Chen   +5 more
doaj   +1 more source

Simulation and Experimental Study on the Inhomogeneity of Mechanical Properties of Aluminum Alloy 7050 Plate

Metals, 2020
In this work, the finite element method simulated the symmetrical hot rolling process of 7050 aluminum alloy plate. The simulation result show that different thickness layers of 7050 aluminum alloy plate experienced different temperature and strain ...
Hai Gong, Xuan Cao, Yaoqiong Liu, Yunxin Wu, Fangmin Jiang, Minghai Zhang   +5 more
doaj   +1 more source

Modulation of nociception by amitriptyline hydrochloride in the Speke’s hinge‐back tortoise (Kiniskys spekii)

Veterinary Medicine and Science, 2021
Background There are limited studies on the utilization of analgesics in testudines. Management of pain in reptiles is by use of analgesics generally used in other vertebrate species.
Christopher M. Makau, Philemon K. Towett, Klas S.P. Abelson, Titus I. Kanui   +3 more
doaj   +1 more source

Changes in the withdrawal latency with a hot-plate test in resiniferatoxin (RTX)-induced neuropathy.

, 2013
Thermal responses were evaluated by the hot-plate test at 52°C in the vehicle (open squares) and RTX groups (filled squares). Withdrawal latencies remained the same in the vehicle group.
Chih-Lung Lin (297428), Hao Chiang (297429), Yu-Lin Hsieh (297427), Yaw-Syan Fu (297430), Sung-Tsang Hsieh (297432), June-Horng Lue (297431)   +5 more
core   +1 more source

The Hot plate technique was used to test the analgesic efficacy of a methanolic extract of E. spinosa leaf, fruit, and stem at a concentration of 250 mg/kg.

, 2022
The Hot plate technique was used to test the analgesic efficacy of a methanolic extract of E. spinosa leaf, fruit, and stem at a concentration of 250 mg/kg.
Tanveer Hussain (413615), Khizar Hayat Bhatti (9596644), Muhammad Ajaib (9981628), Muhammad Azeem (211501), Mehwish Maqbool (9981625), Tauqeer Sardar (11873550), Saiqa Ishtiaq (3623414), Muhammad Ishtiaq (509503), Alia Gul (12475725), Afeera Afreen (13955466), Afsheen Khan (13955463)   +10 more
core   +1 more source