Results 51 to 60 of about 711,966 (308)

Effects of hyperbaric pressure on the oxidative stress status in healthy subjects

Revista Cubana de Medicina Militar, 2023
Introduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress. Objective: To determine the effects of
Phuong Minh Nguyen, Ben Huu Nguyen, Manh Van Phan, Hoan Duy Bui   +3 more
doaj  

Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury

Frontiers in Physiology, 2021
Background: Acute kidney injury (AKI) is one of the most common organ failures following surgery. We have developed a tripeptide mimetic (ANXA1sp) of the parent annexin A1 molecule that shows promise as an organ protectant limiting cellular stress ...
Hagir Suliman, Qing Ma, Zhiquan Zhang, Jiafa Ren, Benjamin T. Morris, Steven D. Crowley, Steven D. Crowley, Luis Ulloa, Jamie R. Privratsky   +8 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

The impact of gamma-radiation on the cerebral- and cerebellar- cortex of male rats’ brain

Brain Research Bulletin, 2022
This study aims to investigate the impact of gamma-radiation on the cerebral- and cerebellar-cortex of rat’s brain. Animals were whole-body exposed to 3 Gy, every 3 days, up to 9 Gy, and sacrificed 1 h, 1, 3, 7 & 10 days post the last radiation-dose.
Fatma Rabia Algeda, Noaman Abdelatief Eltahawy, Shereen Mohamed Shedid, Helen Nicolas Saada   +3 more
doaj   +1 more source

Continuous positive airway pressure as an accurate marker for non‐24‐hour sleep–wake rhythm disorder

Journal of Sleep Research, 2023
SummaryNon‐24‐h sleep–wake rhythm disorder is quite rare in sighted patients and frequently associated with psychiatric disorders. We report the case of a 46‐year‐old man with autism spectrum disorder (ASD) and agoraphobia who had been referred for a suspicion of obstructive sleep apnea syndrome (OSAS).
Balthazar Bazin, Pierre A. Geoffroy, Hélène Benzaquen, Julia Maruani, Alix Romier, Michel Lejoyeux, Marie‐Pia D'ortho, Justine Frija‐Masson   +7 more
openaire   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

P55 TARGET ORGAN DAMAGE AND BLOOD PRESSURE VARIABILITY IN HYPERTENSION

Artery Research, 2017
Purpose/Background/Objectives: Hypertension is associated with several markers of subclinical target organ damage (TOD). Short-term blood pressure variability (SBPV) is a prognostic factor for cardiovascular events in hypertensives.
Dimitrios Terentes-Printzios, Charalambos Vlachopoulos, Athanasios Angelis, Nikolaos Loakeimidis, Panagiotis Xaplanteris, Christos Georgakopoulos, Evangelia Sigala, Losif Koutagiar, Angeliki Rigatou, Dimitrios Tousoulis   +9 more
doaj   +1 more source

GENERATION OF MOUSE INDUCED PLURIPOTENT STEM CELLS BY PROTEIN TRANSDUCTION. [PDF]

, 2013
Somatic cell reprogramming has generated enormous interest after the first report by Yamanaka and his coworkers in 2006 on the generation of induced pluripotent stem cells (iPSCs) from mouse fibroblasts. Here we report the generation of stable iPSCs from
Andras Dinnyes, Csilla Nemes, Eszter Varga, Jalving M., Melinda K. Pirity, Nuttha Klincumhom, Zsuzsanna Polgar   +6 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Potential Surrogate Markers for Gamma-Hydroxybutyrate Administration May Extend the Detection Window from 12 to 48 Hours [PDF]

Journal of Analytical Toxicology, 2007
The exogenous administration of gamma-hydroxybutyrate (GHB) as a drug of abuse, and especially in date rape sexual assaults, has recently increased. Chromatographic techniques are used to detect GHB in blood or urine, with a window of detection limited to 12 h. This brief window makes the proof of administration problematic in most rape cases.
Scott J, Larson, Elizabeth A, Putnam, Corbin M, Schwanke, Mark A, Pershouse   +3 more
openaire   +2 more sources