Results 71 to 80 of about 717,891 (304)

Salsalate treatment improves glycemia without altering adipose tissue in nondiabetic obese hispanics. [PDF]

open access: yes, 2015
ObjectiveSalsalate treatment has well-known effects on improving glycemia, and the objective of this study was to examine whether the mechanism of this effect was related to changes in adipose tissue.MethodsA randomized double-blind and placebo ...
Alderete, Tanya L   +9 more
core   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

MARKERS OF INCREASED RISK OF SUDDEN CARDIAC DEATH IN PATIENTS WITH STABLE ANGINA AND ARTERIAL HYPERTENSION: ASSOCIATION WITH THE PROGRESSION OF LEFT VENTRICULAR HYPERTROPHY

open access: yesРоссийский кардиологический журнал, 2012
Aim. To analyse the markers of sudden cardiac death (SCD) in patients with stable angina and arterial hypertension (AH), in regard to the progression of left ventricular hypertrophy (LVH). Material and methods. In total, 90 patients with Functional Class
M. V. Surovtseva   +3 more
doaj  

A Metabolic Study of Huntington's Disease.

open access: yesPLoS ONE, 2016
BackgroundHuntington's disease patients have a number of peripheral manifestations suggestive of metabolic and endocrine abnormalities. We, therefore, investigated a number of metabolic factors in a 24-hour study of Huntington's disease gene carriers ...
Rajasree Nambron   +12 more
doaj   +1 more source

The role of reactive astrocitose in the chronological evolution of traumatic brain injury [PDF]

open access: yes, 2018
Introduction and objectives. This study aims to investigate whether the cerebral modifications of posttraumatic reactive astrocitose can be considered an objective criterion for determining the age of traumatic cranio-cerebral lesions.
Belis, Vladimir   +5 more
core   +4 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Differences in Inflammatory Markers between Nulliparous Women Admitted to Hospitals in Preactive vs Active Labor [PDF]

open access: yes, 2015
Objective To determine whether labor-associated inflammatory markers differ between low-risk, nulliparous women in preactive vs active labor at hospital admission and over time.
Arntzen   +50 more
core   +2 more sources

Twenty-Four-Hour Heart Rate and Blood Pressure Are Additive Markers of Left Ventricular Mass in Hypertensive Subjects [PDF]

open access: yesAmerican Journal of Hypertension, 2006
We investigated whether mean heart rate (HR(24)) and blood pressure (BP) parameters during 24-h ambulatory BP monitoring (ABP) are independent or additive markers of left ventricular (LV) mass in subjects with newly diagnosed, untreated hypertension.A total of 250 patients (40% women, 60% men; mean age 59.6 +/- 11 years) with essential hypertension who
Zakopoulos, NA   +9 more
openaire   +3 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

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