Results 51 to 60 of about 717,891 (304)
Differentiation of gram-negative bacterial aerosol exposure using detected markers in bronchial-alveolar lavage fluid. [PDF]
PLoS ONE, 2009 The identification of biosignatures of aerosol exposure to pathogens has the potential to provide useful diagnostic information. In particular, markers of exposure to different types of respiratory pathogens may yield diverse sets of markers that can be ...
David Wunschel +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Effects of hyperbaric pressure on the oxidative stress status in healthy subjects
Revista Cubana de Medicina Militar, 2023 Introduction: In the hyperbaric pressure environment the partial pressure of each gas component increases, which increases oxygen partial pressure. This causes the generation of free radicals and oxidative stress. Objective: To determine the effects of
Phuong Minh Nguyen +3 more
doaj
Frontiers in Physiology, 2021 Background: Acute kidney injury (AKI) is one of the most common organ failures following surgery. We have developed a tripeptide mimetic (ANXA1sp) of the parent annexin A1 molecule that shows promise as an organ protectant limiting cellular stress ...
Hagir Suliman +8 more
doaj +1 more source
Journal of Sleep Research, 2023 SummaryNon‐24‐h sleep–wake rhythm disorder is quite rare in sighted patients and frequently associated with psychiatric disorders. We report the case of a 46‐year‐old man with autism spectrum disorder (ASD) and agoraphobia who had been referred for a suspicion of obstructive sleep apnea syndrome (OSAS).
Balthazar Bazin +7 more
openaire +2 more sources
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Disrupted circadian rhythms are associated with cardiometabolic disease. We examined associations between rest‐activity rhythms and cardiometabolic disease by race.
Swaty Chapagai +7 more
doaj +1 more source
The impact of gamma-radiation on the cerebral- and cerebellar- cortex of male rats’ brain
Brain Research Bulletin, 2022 This study aims to investigate the impact of gamma-radiation on the cerebral- and cerebellar-cortex of rat’s brain. Animals were whole-body exposed to 3 Gy, every 3 days, up to 9 Gy, and sacrificed 1 h, 1, 3, 7 & 10 days post the last radiation-dose.
Fatma Rabia Algeda +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
P55 TARGET ORGAN DAMAGE AND BLOOD PRESSURE VARIABILITY IN HYPERTENSION
Artery Research, 2017 Purpose/Background/Objectives: Hypertension is associated with several markers of subclinical target organ damage (TOD). Short-term blood pressure variability (SBPV) is a prognostic factor for cardiovascular events in hypertensives.
Dimitrios Terentes-Printzios +9 more
doaj +1 more source