Results 61 to 70 of about 717,891 (304)

Potential Surrogate Markers for Gamma-Hydroxybutyrate Administration May Extend the Detection Window from 12 to 48 Hours [PDF]

Journal of Analytical Toxicology, 2007
The exogenous administration of gamma-hydroxybutyrate (GHB) as a drug of abuse, and especially in date rape sexual assaults, has recently increased. Chromatographic techniques are used to detect GHB in blood or urine, with a window of detection limited to 12 h. This brief window makes the proof of administration problematic in most rape cases.
Scott J, Larson, Elizabeth A, Putnam, Corbin M, Schwanke, Mark A, Pershouse   +3 more
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Clinical usefulness of cancer markers in primary breast cancer [PDF]

, 2011
The aim of this study was to investigate the diagnostic power of CA 549, MSA and CA 15-3 in identifying breast cancer. The study included 232 patients of which 56 were healthy, 43 had benign breast cancer and 191 with other growths.
Clouth, Aline, Oremek, Gerhard Maximilian, Verring, A., Ziolkowski, Piotr   +3 more
core   +2 more sources

The Effects of a 36-Hour Mixed Task Ultraendurance Race on Mucosal Immunity Markers and Pulmonary Function [PDF]

Wilderness & Environmental Medicine, 2017
Objective The present study was conducted to assess the changes in mucosal immunity and pulmonary function among participants in a 36-hour mixed task ultraendurance race. Methods Thirteen of the 20 race participants volunteered for the investigation (age 34±5 y).
David, Bellar, Kellie A, Murphy, Ritvik, Aithal, Greggory R, Davis, Tim, Piper   +4 more
openaire   +2 more sources

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Values of troponin T and myoglobin predictive of non-cardiac ischemia in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s):Biochemical markers are important for the timely diagnosis and follow-up of ischemic events. Most of the markers have been previously studied in the context of cardiac ischemia.
Orkut Guclu, Ahmet Caliskan, Oguz Karahan, Sinan Demirtas, Suleyman Yazici, Celal Yavuz, Binali Mavitas   +6 more
doaj  

The effect of temperature on the duration of spawning markers—migratory-nucleus and hydrated oocytes and postovulatory follicles—in the multiple-batch spawner Japanese flounder (Paralichthys olivaceus) [PDF]

, 2011
The duration of spawning markers (e.g. signs of previous or imminent spawnings) is essential information for estimating spawning frequency of fish. In this study, the effect of temperature on the duration of spawning markers (i.e., oocytes at early ...
Amano, Masafumi, Fujinami, Yuichiro, Kurita, Yutaka   +2 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Effects of a 48-Hour Fasting Period on Metabolic Markers During Exercise and Recovery in Male Combat Sports Athletes

Baltic Journal of Sport and Health Sciences
Purpose: Fasting strategies have gained increasing attention in sports science due to their potential effects on metabolic responses and athletic performance.
Asya Culhaoglu, Nerijus Eimantas, Rima Solianik, Berta Ylaitė, Marius Brazaitis   +4 more
doaj   +1 more source

Clinical and functional manifestations of hypervolemia in patients with arterial hypertension

Кардиоваскулярная терапия и профилактика, 2011
Aim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold ...
O. B. Poselyugina, S. A. Nilova, V. S. Volkov, Al Galban Hakhed   +3 more
doaj   +1 more source