Results 61 to 70 of about 1,668,878 (290)

Stability of Novel Plasma Markers Associated with Cardiovascular Disease: Processing within 36 Hours of Specimen Collection [PDF]

Clinical Chemistry, 2002
Plasma markers are ideally measured prospectively because marker concentrations may change after diagnosis with disease. In many large prospective studies, such as the Nurses’ Health Study (1) and Health Professionals Follow-up Study (2), blood samples are collected, placed on ice, and mailed back to the central laboratory for processing via overnight ...
Jennifer K, Pai, Gary C, Curhan, Carolyn C, Cannuscio, Nader, Rifai, Paul M, Ridker, Eric B, Rimm   +5 more
openaire   +2 more sources

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

1-Hour OGTT Plasma Glucose as a Marker of Progressive Deterioration of Insulin Secretion and Action in Pregnant Women [PDF]

International Journal of Endocrinology, 2012
Considering old GDM diagnostic criteria, alterations in insulin secretion and action are present in women with GDM as well as in women with one abnormal value (OAV) during OGTT. Our aim is to assess if changes in insulin action and secretion during pregnancy are related to 1-hour plasma glucose concentration during OGTT.
Ghio A, Seghieri G, Lencioni C, Anichini R, BERTOLOTTO, ALESSANDRA, De Bellis A, RESI, VERONICA, LACARIA, EMILIA, DEL PRATO, STEFANO, Di Cianni G.   +9 more
openaire   +4 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

MARKERS OF INCREASED RISK OF SUDDEN CARDIAC DEATH IN PATIENTS WITH STABLE ANGINA AND ARTERIAL HYPERTENSION: ASSOCIATION WITH THE PROGRESSION OF LEFT VENTRICULAR HYPERTROPHY

Российский кардиологический журнал, 2012
Aim. To analyse the markers of sudden cardiac death (SCD) in patients with stable angina and arterial hypertension (AH), in regard to the progression of left ventricular hypertrophy (LVH). Material and methods. In total, 90 patients with Functional Class
M. V. Surovtseva, N. A. Koziolova, A. I. Chernyavina, I. M. Shatunova   +3 more
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

The Effects of a 48-Hour Fasting Period on Metabolic Markers During Exercise and Recovery in Male Combat Sports Athletes

Baltic Journal of Sport and Health Sciences
Purpose: Fasting strategies have gained increasing attention in sports science due to their potential effects on metabolic responses and athletic performance.
Asya Culhaoglu, Nerijus Eimantas, Rima Solianik, Berta Ylaitė, Marius Brazaitis   +4 more
doaj   +1 more source

A Metabolic Study of Huntington's Disease.

PLoS ONE, 2016
BackgroundHuntington's disease patients have a number of peripheral manifestations suggestive of metabolic and endocrine abnormalities. We, therefore, investigated a number of metabolic factors in a 24-hour study of Huntington's disease gene carriers ...
Rajasree Nambron, Edina Silajdžić, Eirini Kalliolia, Chris Ottolenghi, Peter Hindmarsh, Nathan R Hill, Seán J Costelloe, Nicholas G Martin, Vincenzo Positano, Hilary C Watt, Chris Frost, Maria Björkqvist, Thomas T Warner   +12 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Clinical and functional manifestations of hypervolemia in patients with arterial hypertension

Кардиоваскулярная терапия и профилактика, 2011
Aim. To identify clinical and functional manifestations of hypervolemia in patients with arterial hypertension (AH). Material and methods. In total, 440 patients with Stage I-II AH were examined, including assessment of salt taste sensitivity threshold ...
O. B. Poselyugina, S. A. Nilova, V. S. Volkov, Al Galban Hakhed   +3 more
doaj   +1 more source