Results 51 to 60 of about 6,400,597 (307)
Fire simulation in house conditions [PDF]
Tehnika, 2016 Fire simulation presents very powerful, economic and safe way for determination of potential fire scenarious in particular object. Because the fire presents very unpredictable event, it is very important to ,as much is possible, predict its potential ...
Jevtić Radoje B.
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
L’agglomération protohistorique de Chens-sur-Léman. Un modèle d’habitat inédit
Archéopages, 2015 Archaeological excavations carried out between 2009 and 2012 at Chens-sur-Léman (Haute-Savoie) have allowed us to revisit our concepts of Bronze Age settlements.
Sylvie Cousseran-Néré, Éric Néré
doaj +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Une maison mixte médiévale à Roissy-en-France
Archéopages, 2013 Medieval house at Roissy-en-France with a lean-to used as a pigsty, reminding us of the close relationship between humans and pigs up to the time of improvement in hygiene at the end of the 19th century and the beginning of the 20th century.
Jean-Yves Dufour
doaj +1 more source
Bonding, Structure and the Stability of Political Parties: Party Government in the House [PDF]
, 1994 The public policy benefits that parties-deliver are allocated by democratic procedures that devolve ultimately to majority rule. Majority-rule decision making, however, does not lead to consistent policy choices; it is unstable. In this paper, we argue
Cox, Gary W., McCubbins, Mathew D.
core +2 more sources
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
Newsletter / House of Finance, Goethe-Universität Frankfurt 3/09 [PDF]
, 2009 Credit Rating Announcements – The Impact of the Agency’s Reason, Public Information, and M&A ; Toward a New European Financial Architecture in the Rating Sector – an Economic Analysis and Legal Solutions ; Where Finance Meets Macro ; Clear Enforcement ...
House of Finance
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Newsletter / House of Finance, Goethe-Universität Frankfurt 4/10 [PDF]
, 2010 Credit Rating Announcements – The Impact of the Agency’s Reason, Public Information, and M&A ; Toward a New European Financial Architecture in the Rating Sector – an Economic Analysis and Legal Solutions ; Where Finance Meets Macro ; Clear Enforcement ...
House of Finance
core