Results 71 to 80 of about 6,400,597 (307)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Linguistic Realization of the Concept “House/Home” in Yu.V. Trifonov’s Discourse

open access: yesИзвестия Южного федерального университета: Филологические науки, 2018
The increased attention of modern linguistic science to the questions of conceptualization of the surrounding world is due to the fact that V. von Humboldt’s ideas about the interrelation between the language and the character of the people are being ...
Dinara R. Valeeva
doaj   +1 more source

For principled model fitting in mathematical biology

open access: yes, 2014
The mathematical models used to capture features of complex, biological systems are typically non-linear, meaning that there are no generally valid simple relationships between their outputs and the data that might be used to validate them.
House, Thomas
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

ANALISIS MATEMATIS PENGARUH LOKASI RUMAH TERHADAP HARGA JUAL, LUAS RUMAH DAN JUMLAH KAMAR DENGAN MANOVA

open access: yesJurnal Lebesgue
A house is a building that functions as a residence or residence and a means of family development (Law No. 4 of 1992). Every community needs a house as a necessity. With so many people needing a place to live, house construction often occurs.
Annisa Nur Afifah Kusuma Sayekti   +2 more
doaj   +1 more source

Poetic landscapes of Wilhelm Przeczek

open access: yesActa Universitatis Lodziensis. Folia Litteraria Polonica, 2020
Wilhelm Przeczek is a Polish writer who has lived in Karviná, the Czech Republic, since he was born in 1936. He is a member of a Polish minority and he has aimed his literary output at its members and at readers in Poland.
Libor Martinek
doaj   +1 more source

Life sciences flight experiments program, life sciences project division, procurement quality provisions [PDF]

open access: yes
Methods are defined for implementing quality assurance policy and requirements for life sciences laboratory equipment, experimental hardware, integration and test support equipment, and integrated ...
House, G.
core   +1 more source

Algebraic moment closure for population dynamics on discrete structures

open access: yes, 2014
Moment closure on general discrete structures often requires one of the following: (i) an absence of short closed loops (zero clustering); (ii) existence of a spatial scale; (iii) ad hoc assumptions.
House, Thomas
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Devenir un « maître de maison » dans le Sud jordanien

open access: yesAteliers d'Anthropologie, 2015
How does one become a master of the house, a man capable of controlling a kinship network and a family space? This article approaches the logic of power and authority in a tribal area of southern Jordan through its spatial and corporeal dimensions.
Christine Jungen
doaj   +1 more source

Home - About - Disclaimer - Privacy