Results 41 to 50 of about 2,837,475 (309)

Quality evaluation of fresh and bloomed filled chocolates in House of Quality [PDF]

open access: yes, 2011
C
De Clercq, Nathalie   +8 more
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Predicting Quality of Modified Product Attributes to Achieve Customer Satisfaction

open access: yesDesigns
In the era of the competitive environment, the improvement in current products is ensured through activities aimed at increasing a product’s quality level and, consequently, reducing the amount of waste.
Andrzej Pacana, Dominika Siwiec
doaj   +1 more source

Application of a quality function deployment technique to design and develop furniture products [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2012
It is important for furniture manufacturers to develop an effective organization, produce high-quality products, anddevelop new product designs which correlate with customer requirements to obtain more satisfactory output. Quality functiondeployment (QFD)
Chatree Homkhiew   +2 more
doaj  

A fuzzy model for exploiting customer requirements [PDF]

open access: yesManagement Science Letters, 2016
Nowadays, Quality function deployment (QFD) is one of the total quality management tools, where customers’ views and requirements are perceived and using various techniques improves the production requirements and operations.
Zahra Javadirad   +3 more
doaj   +1 more source

Quality of Life - Housing

open access: yes, 2010
Housing is one of the basic needs for well-being. Poor quality of housing may have adverse effects on health and well-being. Housing is one of the basic needs of all individuals, and the standard of housing impacts on physical health and well-being. Housing requiring major repairs inversely affects housing quality, while a high number of people per ...
openaire   +1 more source

Voting in the Bicameral Congress: Large Majorities as a Signal of Quality [PDF]

open access: yes, 2009
We estimate a model of voting in Congress that allows for dispersed information about the quality of proposals in an equilibrium context. The results highlight the effects of bicameralism on policy outcomes.
Iaryczower, Matias   +2 more
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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