Results 31 to 40 of about 405,005 (263)

Collaborative Performance Research on Multi-level Hospital Management Based on Synergy Entropy-HoQ

Entropy, 2015
Because of the general lack of multi-level hospital management collaboration performance effectiveness research, this paper proposes a multi-level hospital management Synergy Entropy-House of Quality (HoQ) Measurement Model by innovatively combining the ...
Lei Chen, Xuedong Liang, Tao Li
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

QFD-based conceptual design of an autonomous underwater robot [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2015
Autonomous underwater robots in the past few years have been designed according to the individual concepts and experiences of the researchers. To design a robot, which meets all the requirements of potential users, is an advanced work.
Thip Pasawang, Theerayuth Chatchanayuenyong, Worawat Sa-Ngiamvibool   +2 more
doaj  

Service user and carer involvement in mental health care safety: raising concerns and improving the safety of services

BMC Health Services Research, 2018
Background Previous research into improving patient safety has emphasised the importance of responding to and learning from concerns raised by service users and carers.
Kathryn Berzins, Gemma Louch, Mark Brown, Jane K. O’Hara, John Baker   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

ENHANCING SERVICE EFFICIENCY IN UTILITY ORGANIZATIONS THROUGH QUALITY FUNCTION DEPLOYMENT

International Journal of Management Studies
Quality Function Deployment (QFD) is a powerful approach for establishing a strong relationship between a product or service and customer needs. It focuses on capturing the voice of the customer to enhance their satisfaction.
Maryam Shahid, Rafiq Mansoor, Muhammad Shahid, Syed Athar Masood   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

INTEGRASI SERVQUAL DAN QUALITY FUNCTION DEPLOYMENT UNTUK PENGUKURAN KUALITAS LAYANAN (STUDI KASUS: PROGRAM STUDI PENDIDIKAN TEKNIK MESIN, UNIVERSITAS PALANGKA RAYA)

Journal of Engineering and Management in Industrial System, 2013
Services in Program Studi Pendidikan Teknik Mesin (PSPTM) still has drawbacks, among other complaints for cleanliness wc, and class. This indicates or identifies a student dissatisfaction against poor service.
Wiyogo Wiyogo, Surachman Surachman, Rudy Soenoko, Nasir Widha Setyanto   +3 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source