Results 51 to 60 of about 4,412 (212)

Integration of Quality Function Deployment and TRIZ Methodologies to Design a Sanitary Part [PDF]

International Journal of Industrial Engineering and Production Research
A typical definition of New Product Development is a series of actions that begins with the identification of a market opportunity and concludes with the creation, marketing, and delivery of a product.
Dino Caesaron, Farell Ardani, Vidhea Nurhadi, Yusuf Yekti   +3 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

IMPLEMENTASI METODE QUALITY FUNCTION DEPLOYMENT (QFD) GUNA MENINGKATKAN KUALITAS KAIN BATIK TULIS

Jurnal Ilmiah Teknik Industri, 2006
Pemilihan dan pengoptimalan suatu metode yang lebih baik untuk meningkatkan mutu suatu produk atau jasa yang dihasilkan sangat diperlukan oleh perusahaan dewasa ini.
Jono Jono
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Designing a model for product planning in quality function deployment using goal programming and analytic network process approach [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2004
QFD starts with the house of quality (HOQ) which is a planning matrix translating the customer needs into measurable product technical requirements (PTRs). As with any other tool the quantum of benefits obtained from the use of QFD is proportional to the
M. Momeni, A. Atashsooz
doaj  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

From House of Quality to Neural Architecture: Quality-Informed Neural Networks for Interpretable Classification, with an EU AI Act Compliance Application

Systems
As software systems increasingly combine machine learning, deep learning, and generative AI components with classical deterministic logic, the systematic detection of AI-based algorithmic elements in application code is becoming essential for software ...
Andreea Ionica, Monica Leba
doaj   +1 more source

Designing and improvement of quality function development (fuzzy Kano approach) [PDF]

Muṭāli̒āt-i Mudīriyyat-i Ṣan̒atī, 2012
One of the trench that is used in quality desiccation is QualityFunction Deployment. One of the factors which has been used in thismethod is accomplishing the house of quality and as a result isdetermining the degree of importance of the customer's ...
Adel Azar, Maryam Shariati rad
doaj  

Analisis Anggaran Belanja Makanan dalam Menentukan Standar Gizi Pasien Rawat Inap di Rumah Sakit PKU Muhammadiyah Gamping

Benefit Jurnal Manajemen dan Bisnis, 2020
This research aims to find out how to analyze the quality of the services of a services company integrated with the SERVQUAL (Service Quality) and the Kano Model into the Quality Function Deployment (QFD) in the Clinic Midwife Ides that have decreased ...
Merita Bernik, Fanisa Putri
doaj   +1 more source