Results 31 to 40 of about 186,828 (260)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

House of Marketing Quality Using the House of Quality to Develop Marketing Strategies

open access: yesJournal of Business & Economics Research (JBER), 2011
The paper presents a Model for Customer Oriented Marketing Strategies, using the House of Quality Approach. The model is presented with an example of Spinning Machinery Marketing.
Bayram Aslan, Helmut H. Hergeth
openaire   +2 more sources

Ranking of Urban Areas in Terms of Quantitative and Qualitative Housing Indicators (Case Study: 22 Regions of Arak City) [PDF]

open access: yesمطالعات جغرافیایی مناطق خشک
Aim: This research attempts to rank the 22 districts of Arak based on quantitative and qualitative housing indicators and to identify the spatial distribution pattern of these indicators at the city level. Material & Method: Subsequently, using Shannon's
Hossein Hataminejad   +2 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Semi-open urban blocks and convertible apartments: A-4 residential buildings in Novi Sad, awarded the Borba prize for architecture [PDF]

open access: yesArhitektura i Urbanizam
The article examines the architectural and urban characteristics of the residential building (type A-4), which was designed during the implementation of the Novo Naselje urban project in Novi Sad in the 1970s. The authors were architects Slavko Županski,
Antešević Nebojša, Gubić Ilija
doaj   +1 more source

An Analysis of spatial inequalities of Housing quality in middle textures neighboods of zanjan city [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2021
Housing as one of the basic human needs a significant impact on the health and improve the quality of life of individuals. The quality of housing as one of the main foundations of a comprehensive program and a necessary tool for expressing the various ...
Mohsen Ahadnejad   +3 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Valorization of calcined Egyptian marble waste as a reactive CaO additive for fortifying alkali-activated slag cement

open access: yesJournal of Engineering and Applied Science
Egypt’s thriving marble industry produces extensive waste marble powder (WMP) amounts. Recycling plentiful waste safely and effectively is a key national concern, as improper disposal poses a serious threat to the environment.
Alaa M. Rashad   +3 more
doaj   +1 more source

Les multiples facettes des inégalités écologiques

open access: yesDéveloppement Durable et Territoires, 2007
The notion of ecological inequalities is understood in very different ways depending on different cultural contexts. In the United States, where it has first developed, its only meaning is in an action perspective.
Lionel Charles   +5 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

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