Results 31 to 40 of about 187,221 (258)

Sociodemographic Factors Associated With Later Stage at Diagnosis of Pediatric Germ Cell Tumors: A Report From Children's Oncology Group Registries ACCRN07 and APEC14B1

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Germ cell tumors (GCTs) often arise in the ovaries and testes (extracranial) but can also develop in the brain (intracranial). We examined the relationship of individual, family, and community‐level socioeconomic status (SES) with stage of disease at diagnosis in a cohort of pediatric patients with GCT from Children's Oncology Group
Heydon K. Kaddas   +7 more
wiley   +1 more source

Ranking of Urban Areas in Terms of Quantitative and Qualitative Housing Indicators (Case Study: 22 Regions of Arak City) [PDF]

open access: yesمطالعات جغرافیایی مناطق خشک
Aim: This research attempts to rank the 22 districts of Arak based on quantitative and qualitative housing indicators and to identify the spatial distribution pattern of these indicators at the city level. Material & Method: Subsequently, using Shannon's
Hossein Hataminejad   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Valorization of calcined Egyptian marble waste as a reactive CaO additive for fortifying alkali-activated slag cement

open access: yesJournal of Engineering and Applied Science
Egypt’s thriving marble industry produces extensive waste marble powder (WMP) amounts. Recycling plentiful waste safely and effectively is a key national concern, as improper disposal poses a serious threat to the environment.
Alaa M. Rashad   +3 more
doaj   +1 more source

Les multiples facettes des inégalités écologiques

open access: yesDéveloppement Durable et Territoires, 2007
The notion of ecological inequalities is understood in very different ways depending on different cultural contexts. In the United States, where it has first developed, its only meaning is in an action perspective.
Lionel Charles   +5 more
doaj   +1 more source

An Analysis of spatial inequalities of Housing quality in middle textures neighboods of zanjan city [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2021
Housing as one of the basic human needs a significant impact on the health and improve the quality of life of individuals. The quality of housing as one of the main foundations of a comprehensive program and a necessary tool for expressing the various ...
Mohsen Ahadnejad   +3 more
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Egyptian basalt powder as a fortifier for improved performance and sustainability of alkali-activated slag cement

open access: yesScientific Reports
As is well established, slag precursor offers promising performance characteristics; however, its origin as an industrial byproduct leads to variability in both mineralogical and chemical composition.
Alaa M. Rashad   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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