Results 51 to 60 of about 187,221 (258)

Sustainable housing: Analysis of energy performance potential in Turkey with translation of building standards of Austria

Građevinar, 2022
This study aims to investigate the energy-saving potential in the housing sector and encourage the employment of energy-efficient applications in Turkey by adapting the current European building techniques, policies and building standards in the Turkish ...
Hatice Kalfaoglu Hatipoglu, Rukiye Cetin, Atilla Hatipoglu   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Post-Occupancy Assessment of the Operational Performance of Low-Cost Housing in Ethiopia: A Case Study of Bishoftu City

Ethiopian Journal of Science and Sustainable Development
Ethiopia faces a critical housing shortage, particularly in rapidly urbanizing cities such as Bishoftu, where population growth and expansion have increased demand for affordable housing.
Lemma Beressa Gudeta, Zerihun Mamo Asamenew, Olana Tesfaye Hunde   +2 more
doaj   +1 more source

Calitatea condiţiilor de locuire în România, în perioada post-aderare la U.E. [PDF]

Urbanism. Arhitectura. Constructii, 2012
This study contains a post-adhering to European Union diagnosis of housing conditions. Statistics provided by the European Union Statistics Network, Eurostat, highlight the precariousness of housing quality, the main element of the quality of life ...
Daniel-Gabriel Vâlceanu, Diana-Georgiana Tămîrjan   +1 more
doaj  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Correlation of Housing Quality Indices and Perceived Stress in Isfahan Metropolis’ Families

تحقيقات جغرافيايی, 2019
Aims & Backgrounds: Based on WHO research, a long range of mental disorders in developing countries and developed countries are related to economic status of a country. Stress is one of the most important mental disorders.
Seyed Reza Azadeh, Jamal Mohammadi, Hamid Taher Neshat Dost   +2 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Evaluating Apartment Satisfaction in Erbil City: The Impact of Interior Space Quality Indicators before, during, and after the COVID-19 Pandemic

Buildings
Human existence and development have always relied on suitable shelter. The dual-directional relationship of human residence has always been a material dealt with to enhance residential living conditions. The emergence of the COVID-19 pandemic introduced
Nazik Jamal Abdulhamid, Hasan Abdulrazzaq Hasan Al-Sanjary   +1 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Spatial Zoning of Housing Quality by Combining CRITIC Weighting Method and Fuzzy Logic; Case Study: Qaen City [PDF]

مطالعات جغرافیایی مناطق خشک
Aims: The purpose of this research is to zone housing quality in Qaen city spatially. Materials & Methods: The statistical population of the research is the statistical blocks of Qaen city.
Saeed Hossein Abadi
doaj   +1 more source