Results 131 to 140 of about 27,788 (178)
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The International Journal of Developmental Biology, 1994
During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column.
A E, Carrasco, S L, López
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During the last few years, the regionalization of the rostral-caudal axis has been extensively studied through treatments with RA and genetic manipulations of Hox-C genes. RA shifts several Hox expression boundaries rostrally, deletes anterior rhombomeres but expands the caudal ones, and induces homeotic transformations in the vertebral column.
A E, Carrasco, S L, López
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Endocrine Regulation of HOX Genes [PDF]
Endocrine Reviews, 2006 Hox genes have a well-characterized role in embryonic development, where they determine identity along the anteroposterior body axis. Hox genes are expressed not only during embryogenesis but also in the adult, where they are necessary for functional differentiation.
Hugh S. Taylor, Gaurang S Daftary
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The Hox Genes and Their Roles in Oncogenesis
Nature Reviews Cancer, 2010Hox genes, a highly conserved subgroup of the homeobox superfamily, have crucial roles in development, regulating numerous processes including apoptosis, receptor signalling, differentiation, motility and angiogenesis. Aberrations in Hox gene expression have been reported in abnormal development and malignancy, indicating that altered expression of Hox
Saraswati Sukumar, Nilay Shah
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Seminars in Cell and Developmental Biology, 1999
The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
Edmund J Stellwag
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The study of Hox gene clusters continues to serve as a paradigm for those interested in vertebrate genome evolution. Recent exciting discoveries about Hox gene composition in fishes challenges conventional views about vertebrate Hox gene evolution, and has initiated lively debates concerning the evolutionary events making the divergence of the major ...
Edmund J Stellwag
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2014
How transcription is controlled by distally located cis regulatory elements is an active area of research in biology. As such there have been many techniques developed to probe these long distance chromatin interactions. Here we focus on one such method called DamID (van Steensel and Henikoff Nat Biotechnol 18(4):424 428 2000). While other methods like
Cléard Fabienne +2 more
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How transcription is controlled by distally located cis regulatory elements is an active area of research in biology. As such there have been many techniques developed to probe these long distance chromatin interactions. Here we focus on one such method called DamID (van Steensel and Henikoff Nat Biotechnol 18(4):424 428 2000). While other methods like
Cléard Fabienne +2 more
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Hox genes in a pentameral animal
BioEssays, 2001There is renewed interest in how the different body plans of extant phyla are related. This question has traditionally been addressed by comparisons between vertebrates and Drosophila. Fortunately, there is now increasing emphasis on animals representing other phyla.
E, Popodi, R A, Raff
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The FASEB Journal, 1996
The vertebrate embryonic body plan is constructed through the interaction of many de‐ velopmentally regulated genes that supply cells with the essential positional and functional information they require to migrate to their appropriate destination and generate the proper structures.
H, Marshall +4 more
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The vertebrate embryonic body plan is constructed through the interaction of many de‐ velopmentally regulated genes that supply cells with the essential positional and functional information they require to migrate to their appropriate destination and generate the proper structures.
H, Marshall +4 more
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Hox genes and animal regeneration
Russian Journal of Developmental Biology, 2016The concept of regeneration is intimately associated with ideas about positional information, that is, the distribution of various signals prescribing cells their location in an embryo or an adult organism. Hox genes are perfect candidates for the role of factors creating positional information.
E L, Novikova +3 more
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Hox genes and the making of sphincters
Nature, 1999Hoxd genes are needed for the formation of sphincters to subdivide the developing gut. As well as their shared role in the anteroposterior patterning of vertebrates1, particular Hox gene com-plexes have evolved specific functions. For example, four consecutive genes of the HoxD cluster contribute to making proper digits2,3.
Zakany, J., Duboule, D.
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Hox genes and kidney development
Pediatric Nephrology, 2011The adult mammalian kidney is generated by the differentiation and integration of several distinct cell types, including the nephrogenic mesenchyme, ureteric epithelium, stromal and endothelial cells. How and where these cell types are generated and what signals lead to their differentiation and integration into a functional organ system is a main ...
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