Results 61 to 70 of about 339,718 (373)

A Non-Invasive Strategy for Neonatal Alloimmune Thrombocytopenia Diagnosis: Newborn Platelet Genotyping with Buccal Swabs

International Journal of Neonatal Screening, 2016
Neonatal alloimmune thrombocytopenia results from the maternal immune response against fetal-specific antigens inherited from the father. The diagnosis is ascertained only when the maternal alloantibody and the offending antigen present in the newborn ...
Gérald Bertrand, Cécile Kaplan
doaj   +1 more source

Maternal incompatibilities with fetal human platelet alloantigens -1a, -1b and -15 are the main causes of neonatal alloimmune thrombocytopenia in Russia [PDF]

Терапевтический архив, 2018
The aim. Mechanisms underlying the development of neonatal alloimmune thrombocytopenia (NAIT) in in Russia have been studied. Materials and methods. Genetic polymorphisms of human platelet alloantigens (HPA) -1, -2, -3, -4, -5, and -15 were evaluated in ...
S G KHASPEKOVA, L L GOLOVKINA, E K DONUSH, N V GOLUBEVA, O N SHUSTOVA, A V MAZUROV   +5 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Frequency of human platelet antigens in oncohematological patients with thrombocytopenia and the probability of incompatibility to platelet transfusions Frequência dos antígenos plaquetários humanos (HPA) em pacientes trombocitopênicos e predisposição à incompatibilidade transfusional

Revista Brasileira de Hematologia e Hemoterapia, 2012
OBJECTIVE: The objective of this study was to evaluate the frequencies of human platelet antigens in oncohematological patients with thrombocytopenia and to analyze the probability of their incompatibility with platelet transfusions.
Juliana Vieira dos Santos Bianchi, Maria Regina Andrade de Azevedo, Eduardo Jens, Youko Nukui, Dalton Alencar Ficher Chamone   +4 more
doaj   +1 more source

Stress and the HPA Axis: Balancing Homeostasis and Fertility

International Journal of Molecular Sciences, 2017
An organism’s reproductive fitness is sensitive to the environment, integrating cues of resource availability, ecological factors, and hazards within its habitat.
Dana N. Joseph, Shannon D. Whirledge
semanticscholar   +1 more source

Orbiter based construction equipment [PDF]

, 1982
Many orbiter based activities need equipment to hold a payload steady while it is being worked on. This work may be construction, updating, repair, services, check out, or refueling operations in preparation for return to Earth.
Goodwin, C. J.
core   +1 more source

New Onset of Fibromyalgia After Exposure to a Combat Environment: A Longitudinal Cohort Study

Arthritis Care &Research, Accepted Article.
Objective Traumatic life events are hypothesized to be triggers for the onset of fibromyalgia. Posttraumatic stress disorder (PTSD) is a common comorbidity of fibromyalgia. However, limited prospective data are available on the development of fibromyalgia after exposure to high magnitude stress.
Jay B. Higgs, Willie J. Hale, Casey L. Straud, Jim Mintz, Stacey Young‐McCaughan, Kimberly D. Gomes, Chelsea J. Sterne, Katrina M. Lawrence‐Wolff, Alan J. Bartholomew, Kevin M. Kelly, Douglas M. Maurer, Catherine Vriend, Brett T. Litz, Douglas E. Williamson, Alan L. Peterson, for the STRONG STAR Consortium   +15 more
wiley   +1 more source

Amentadione from the Alga Cystoseira usneoides as a Novel Osteoarthritis Protective Agent in an Ex Vivo Co-Culture OA Model

Marine Drugs, 2020
Osteoarthritis (OA) remains a prevalent chronic disease without effective prevention and treatment. Amentadione (YP), a meroditerpenoid purified from the alga Cystoseira usneoides, has demonstrated anti-inflammatory activity. Here, we investigated the YP
Nuna Araújo, Carla S. B. Viegas, Eva Zubía, Joana Magalhães, Acácio Ramos, Maria M. Carvalho, Henrique Cruz, João Paulo Sousa, Francisco J. Blanco, Cees Vermeer, Dina C. Simes   +10 more
doaj   +1 more source

Atmospheric temperature tides in the tropical upper troposphere and lower stratosphere [PDF]

, 2012
Atmospheric thermal tides are global-scale waves with periods that are harmonics of a solar day, mainly excited by diurnally varying diabatic heating in the troposphere and the stratosphere.
Sakazaki, Takatoshi
core   +1 more source

Microclimate variations between semienclosed and open sections of a marathon route [PDF]

, 2013
The Hong Kong Standard Chartered Marathon, held annually, is one of the most popular international marathon events. Its primarily urban environmental setting characterized by high-density urban areas, semienclosed tunnels, and suspension bridges ...
HART, Melissa, LAI, Poh Chin, WONG, Pui Yun, Paulina   +2 more
core   +3 more sources