Results 151 to 160 of about 927,205 (366)
Advanced Healthcare Materials, EarlyView.This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth +10 more
wiley +1 more source
HPLC Analysis of Alkaloids in Extracts of Callus Cultures of Cinchona Species [PDF]
, 1984 Robert Verpoorte +4 more
openalex +1 more source
Cross Metathesis Assisted Solid-Phase Synthesis of Glycopeptoids [PDF]
, 2012 A solid-phase synthesis of glycopeptoids was explored through olefin cross metathesis (CM). Peptoids and sugar derivatives with appropriate olefin moieties were coupled in the presence of an olefin metathesis catalyst to afford glycopeptoids in good ...
Grubbs, Robert H. +3 more
core +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
3-Hydroxy Retinal, a New Chromophore Identified in Insect Eyes: HPLC Separation and NMR Spectroscopic Identification of the Oxime Forms [PDF]
, 1988 Wolfgang Gärtner, Anette Plangger
openalex +1 more source
Advanced Materials, EarlyView.A novel one‐shot integration electropolymerization (OSIEP) method is developed as a breakthrough on the intricate photolithographic steps, enabling to compress all processes from synthesis to channel integration in one‐shot manufacturing. The specially designed dual bipolar electrodes provide the targeted depositions of poly(3,4‐ethylenedioxythiophene)
Jiyun Lee +9 more
wiley +1 more source
HPLC-Determination of Apomorphine in a Mormyrid Fish, Gnathonemus petersii [PDF]
, 1989 Angela M. Noe, Peter C. Kunze
openalex +1 more source
Determination of Tramadol in human plasma by HPLC with fluorescence detection [PDF]
, 2016 Tramadol is a centrally acting analgesic, atypical opioid, and although it is generally considered as a medicinal drug with a low potential for dependence, there is growing evidence of tramadol abuse in some countries.
Abdul Jalil Ebrahim, Zainab +4 more
core +2 more sources
Off‐The‐Shelf Multivalent Nanoconjugate Cancer Vaccine Rescues Host Immune Response against Melanoma
Advanced Materials, EarlyView.A star‐shaped cross‐linked polyglutamate (StCl) nanocarrier delivers melanoma‐associated peptide antigens via redox‐responsive linkers, inducing lymph node‐targeted antigen presentation. The nanoconjugate activates dendritic cells, promotes effector T‐cell responses, and enables tumor regression even in humanized patient‐derived preclinical models ...
Liane IF Moura +19 more
wiley +1 more source
Advanced Materials, EarlyView.Lipid nanoparticles (LNPs) of unconventional composition and defined structures are investigated as small oligonucleotide carriers. A composition is identified that outperforms Onpattro in cargo delivery to HeLa cells. The structure of these LNPs resembles a micellar cubic phase not commonly associated with high‐performing LNPs.
Miina Ojansivu +9 more
wiley +1 more source