Results 11 to 20 of about 308,789 (237)
Background: Persistent infection with human papillomavirus (HPV) can lead to cervical cancer (CxCa). During the progression to CxCa, the expression of HPV oncogenes E6 and E7 is upregulated. In turn, cellular proteins such as p16INK4a are also modulated.
Anna Sophie Skof +5 more
doaj +1 more source
Enhancement of specific T-lymphocyte responses by monocyte-derived dendritic cells pulsed with E2 protein of human papillomavirus 16 and human p16INK4A [PDF]
Introduction Prophylactic vaccines are already available for prevention of human papillomavirus (HPV) infection. However, we still await development of therapeutic vaccines with high efficiency for stimulating specific T lymphocytes to clear HPV ...
Nuchsupha Sunthamala +8 more
doaj +2 more sources
Special Issue: HPV and HPV Vaccines [PDF]
Our fundamental understanding of papillomaviruses and their interactions with their host, including their role in cancer and how the immune system responds to them, has made the elimination of cervical cancer a realistic global health goal [...]
openaire +3 more sources
TLR9 and Glioma: Friends or Foes?
Toll-like receptor 9 (TLR9) is an intracellular innate immunity receptor that plays a vital role in chronic inflammation and in recognizing pathogenic and self-DNA in immune complexes. This activation of intracellular signaling leads to the transcription
Emna Fehri +4 more
doaj +1 more source
The COVID-19 pandemic has exacerbated the existing challenges to achieving the WHO target of eliminating cervical cancer as a public health problem by working towards the target of fewer than four cases per 100 000 women.
Jieying Lee +4 more
doaj +1 more source
Optimization of technical parameters that influence the performance of human papillomavirus (HPV) testing on self-taken samples is important. Here, the authors assessed the impact of resuspension volume on the detection of HPV using four validated HPV ...
Linzi Connor +5 more
doaj +1 more source
Hemorragia Alveolar Difusa - a propósito de um caso clÃnico de Hemossiderose Pulmonar Idiopática.
RESUMO: Devido à sua raridade, a Hemorragia Alveolar Difusa (HAD) é muitas vezes urn diagnóstico esquecido. Os autores apresentam uma revisião desta entidade a propósito do caso clÃnico de um homem de 71 anos, internado por febre, tosse seu ...
Paula Esteves +6 more
doaj +1 more source
Epidemiology of Any and Vaccine-Type Anogenital Human Papillomavirus Among 13-26-Year-Old Young Men After HPV Vaccine Introduction [PDF]
PURPOSE: The aims of this study were to determine prevalence of and factors associated with any human papillomavirus (HPV) and vaccine-type HPV among young men after vaccine introduction, stratified by vaccination status.
Bernstein, David I. +7 more
core +1 more source
RESUMO: No presente caso clÃnico descreve-se um doente com poliserosite, trombocitopénia autoimune e artrite não erosiva. Apresenta ainda lesões cutâneas sugestivas, mas não suficientemente expressivas para a sua inclusão nos critérios de Lupus ...
Carlos Boinas +3 more
doaj +1 more source
Identification of human papillomavirus DNA in cutaneous lesions of Cowden syndrome [PDF]
Background: Cowden syndrome (CS) or multiple hamartoma syndrome is a cancer-associated genodermatosis inherited in an autosomal dominant pattern. One of the diagnostic criteria is facial papules which are felt to be trichilemmomas, benign hair follicle ...
Burgdorf, Walter H. C. +4 more
core +1 more source

