Results 131 to 140 of about 9,143 (202)

Access to diagnosis using liquid biopsy (ADLiB): Identifying lymphoma in a tuberculosis‐endemic setting

HemaSphere, Volume 10, Issue 6, June 2026.
Abstract In HIV‐ and tuberculosis (TB)‐endemic regions, lymphoma diagnosis is often delayed because symptoms can overlap with TB, and access to biopsy and specialized pathology is limited. To address this, we developed and internally evaluated the Access to Diagnosis using Liquid Biopsy (ADLiB) platform—a plasma cell‐free DNA (cfDNA)‐based approach ...
Katherine Antel, Nina Xiong, Mwanasha Merrill, Taiyang Chen, Lauren McGrath, Clara Droessler, Maxine van der Schyff, Meng‐Xuan Wu, Dylan Cheddie, Charlotte Slome, Liam McBride, Jonathan Day, Zainab Mohamed, Nazia Fakie, Nomonde Mbatani, Charlotte Shultz, Graeme Meintjes, Svitlana Tyekucheva, Elizabeth F. Cohen, Michael Y. Tolstorukov, Estelle Verburgh, Mark A. Murakami   +21 more
wiley   +1 more source

The Association Between Human Papillomavirus Type 16 E6 Seroprevalence and Degrees of Anal Disease Among Men With HIV: A Nested Case Control Study

Cancer Control
Introduction Human papillomavirus type 16 (HPV16) E6 antibodies may be an early biomarker of anal cancer. We cross-sectionally evaluated when in the course of anal disease, HPV16 antibodies are induced.
Krystle A. Lang Kuhs PhD, Christopher Otieno MPH, Staci Sudenga PhD, Tim Waterboer PhD, Weiqun Tong MS, Dorothy Wiley PhD, Jay H. Bream PhD, Steven Wolinsky MD, Jeremy Martinson DPhil, Gypsyamber D’Souza PhD   +9 more
doaj   +1 more source

Assessment of correlation between pSTAT3 with HPV16 viral load and E2: E6 Ratio in HPV16-positive cervical tissues (n = 130).

, 2019
Assessment of correlation between pSTAT3 with HPV16 viral load and E2: E6 Ratio in HPV16-positive cervical tissues (n = 130).
Sutapa Mahata (434793), Shirish Shukla (383736), Bhudev Chandra Das (7349036), Kulbhushan Thakur (7349030), Seemi Farhat Basir (7349033), Alok Chandra Bharti (7349039), Mohit Jadli (7349027), Gauri Shishodia (434794)   +7 more
core   +1 more source

Human Papillomavirus: Update in Bridging Basic Science to Clinical and Public Health Innovations

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Human papillomavirus (HPV), a non‐enveloped, double‐strand DNA viral pathogen, is intricately linked with the onset of various cancers, including cervical cancer and head and neck cancers. The present paper delves into HPV's ancient recognition and significant milestones such as the discovery of its role in oncogenesis and the development of ...
Fatemeh Beygnejad, Narges Eslami, Kaveh Gharaei Nejad, Atefeh Zamani Kermanshahi, Hossein Bannazadeh Baghi   +4 more
wiley   +1 more source

HPV16 recruitment of SMARCAL1 to viral and host replication forks is required for the viral life cycle

mBio
High-risk human papillomaviruses (HR HPVs) are responsible for around 5% of the world’s cancer burden. Activation and interaction with the host DNA damage response (DDR) promote the HPV16 life cycle.
Claire D. James, Aya H. Youssef, Jenny D. Roe, Floriana Cappiello, Francesca Antonella Aiello, Benedetta Perdichizzi, Rachel L. Lewis, Austin Witt, Apurva T. Prabhakar, Xu Wang, Molly L. Bristol, Pietro Pichierri, Iain M. Morgan   +12 more
doaj   +1 more source

Mucosal Vaccination with a Recombinant Salmonella typhimurium Expressing Human Papillomavirus Type 16 (HPV16) L1 Virus-like Particles (VLPs) or HPV16 VLPs Purified from Insect Cells Inhibits the Growth of HPV16-Expressing Tumor Cells in Mice

, 2001
Human papillomaviruses, mainly type 16 (HPV16), are responsible for cervical intraepithelial neoplasia, which can lead, in association with other factors, to cervical cancer.
Nardelli-Haefliger, Denise, Schiller, J. T., De Grandi, P., Nardelli-Haefliger, D., Revaz, Véronique, De Grandi, Pierre, Schiller, John T, Kast, W.Martin, Benyacoub, J., Kast, W. M., Benyacoub, Jalil, Revaz, V.   +11 more
core   +1 more source

Primary Cancer Prevention Through Vaccination: Advances, Challenges, and Global Perspectives

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Oncogenic viral and bacterial infections constitute a significant portion of the global cancer burden, accounting for up to 15% of cases, particularly in low‐ and middle‐income countries. Prophylactic vaccination thus appears to be the most effective tool for preventing these preventable cancers, especially those linked to human papillomavirus
Christian Tague, Johan Domga, Ayesha Junaid, Okhesomi Rejoice Eshemokhai, Josias Kamgang Silatchom, Criss Koba Mjumbe   +5 more
wiley   +1 more source

Detection of HPV16 L2-specific antibodies in Balb/c mice vaccinated with AAVLP(HPV16/31L2).

, 2013
Mice were immunized with low dose of AAVLP(HPV16/31L2) particles either twice (LD+M 2x) or three times (LD+M 3x) i.m. together with montanide ISA51 as an adjuvant.
Uwe Michaelis (318085), Mirko Ritter (318080), Markus Hörer (318084), Peter Sehr (77233), Jürgen A. Kleinschmidt (318087), Hanna Seitz (16204), Markus Kellner (318082), Martin Müller (63583), Lutz Gissmann (265124), Sebastian Sedlmeier (318081), Margit Weghofer (318079), Balasubramanyam Karanam (278680), Richard B. S. Roden (278684), Karen Nieto (265118)   +13 more
core   +1 more source

Th17 cells favor migration and invasiveness of cervical cancer cells under hypoxia in an IGF2BP2‐dependent manner

International Journal of Cancer, Volume 158, Issue 11, Page 3021-3037, 1 June 2026.
What's new? Hypoxic regions and inflammatory Th17 cells in the tumor environment are both associated with poor prognosis in cervical cancer. However, synergistic mechanisms between hypoxia and Th17 cells remain elusive. This study demonstrated Th17–hypoxia‐driven mechanisms underlying cervical cancer progression.
Selina Gies, Maike Pohlers, Tanja Tänzer, Emmanuel Ampofo, Matthias W. Laschke, Moritz Schäfer, Yoo‐Jin Kim, Rainer Maria Bohle, Erich‐Franz Solomayer, Konrad Wagner, Martin Empting, Alexandra K. Kiemer, Barbara Walch‐Rückheim   +12 more
wiley   +1 more source

Characterization of patient-derived HPV16 E6 and E7 variant alleles

Journal of Virology
Human papillomavirus type 16 (HPV16) is the most prevalent carcinogenic HPV type. Many HPV16 sequence variants have been described, some of which cause protein-coding mutations.
Miranda Grace, Harshita Beeravolu, Ahmad Alhamshari, Josipa Skelin, Si-Young Kiessling, Andrew Bohm, Elizabeth A. White, Karl Munger   +7 more
doaj   +1 more source