Results 61 to 70 of about 9,143 (202)

Plant Virus Immunotherapy for HPV‐Associated Oropharyngeal Squamous Cell Carcinoma

Advanced NanoBiomed Research, EarlyView.
Cowpea mosaic virus (CPMV) nanoparticles are safe and potent cancer immunotherapy candidates with strong immunomodulatory activity. CPMV activates innate immunity, which in turn drives adaptive immune responses and promotes durable, systemic antitumor effects.
Jessica Fernanda Affonso de Oliveira, Patrick Opdensteinen, Andrea Simms, Seongwon Jung, Giuliana P. Mognol, Hui Chen, Judith A. Varner, Nicole F. Steinmetz   +7 more
wiley   +1 more source

Development of AAVLP(HPV16/31L2) particles as broadly protective HPV vaccine candidate. [PDF]

PLoS ONE, 2012
The human papillomavirus (HPV) minor capsid protein L2 is a promising candidate for a broadly protective HPV vaccine yet the titers obtained in most experimental systems are rather low.
Karen Nieto, Margit Weghofer, Peter Sehr, Mirko Ritter, Sebastian Sedlmeier, Balasubramanyam Karanam, Hanna Seitz, Martin Müller, Markus Kellner, Markus Hörer, Uwe Michaelis, Richard B S Roden, Lutz Gissmann, Jürgen A Kleinschmidt   +13 more
doaj   +1 more source

Regulation of HPV16 Early Gene Expression [PDF]

, 2021
Human papillomavirus type 16 (HPV16) is the most common high-risk type and isassociated with more than 50% cervical cancer cases as well as a number of headand neck cancer cases.
Zheng, Yunji
core  

High levels of HPV16-L1 antibody but not HPV16 DNA load or integration predict oropharyngeal patient outcome: The Papillophar study

, 2023
International audienceThe incidence of oropharyngeal cancers (OPC) is increasing in the world. Among OPC, those induced by human papillomaviruses have a better prognosis than non-HPV-associated OPC.
Lefevre, M., Prétet, Jean-Luc, Mauvais, O., Beby-Defaux, Agnès, Lacau Saint Guily, Jean, Agius, G., Debry, C., Soussan, Patrick, Baglin, A., Hourseau, M., Merol, J., Malard, O., Zalcman, E. Lechapt, Rousseau, Alexandra, Cassagneau, E., Badoual, C., Badet, J., Diebold, M., Touzé, Antoine, Birembaut, Philippe, Mechine, A., Levillain, P., Périé, S., de Raucourt, D., Blanc-Fournier, K., Babin, E., Morinière, S., Mougin, Christiane, Albert, S., Jacquin, Élise, Clavel, Christine, Dufour, X., Rousselot, C., Simon, T., Dalstein, Véronique, Lacave, R., Mirghani, H.   +36 more
core   +1 more source

HPV16 viral characteristics in primary, recurrent and metastatic vulvar carcinoma

Papillomavirus Research, 2018
Vulvar carcinoma is the fourth most common gynecological malignancy. Two separate carcinogenic pathways are suggested, where one is associated with the human papillomavirus (HPV) and HPV16 the most common genotype.The aim of this study was to evaluate ...
Gabriella Lillsunde Larsson, Malin Kaliff, Bengt Sorbe, Gisela Helenius, Mats G. Karlsson   +4 more
doaj   +1 more source

HPV16 E6 is necessary for the stable maintenance of HPV16 as an extrachromosomal genome.

, 2013
Shown are HPV16-specific Southern analyses of total genomic DNA isolated from early (A and B, passage 2) or late (C, passage 6 or higher) NIKS transfected with the indicated wild-type or E6 mutant HPV16 genomes (lanes labeled with the symbol “-” were ...
Paul F. Lambert (266676), Laurel D. Lorenz (476549), Jessenia Rivera Cardona (476550)   +2 more
core   +1 more source

MultNAT HPV16/18 Assay: A Simple, Rapid, and Low‐Cost Polymerase Chain Reaction Method for the Detection of HPV16 and HPV18 Suitable for Point‐of‐Care Testing

Cancer Nexus, EarlyView.
ABSTRACT Aim Persistent high‐risk HPV infection can lead to the development of precancerous lesions, potentially progressing to invasive cancer. HPV status serves not only as a prognostic marker for squamous cell carcinoma (HNSCC) like oropharyngeal squamous cell carcinomas (OPSCC) but also significantly influences clinical management and treatment ...
Min Wang, Yueping Li, Qingting Bu, Peng Xiong, Suhang Li, Xiaoyan Li, Sisi Chen, Yanqiong Zhou, Siyu Li, Xiaojuan Jia   +9 more
wiley   +1 more source

Detection of Circulating HPV16 DNA as a Biomarker for Cervical Cancer by a Bead-Based HPV Genotyping Assay

Microbiology Spectrum, 2022
Human papillomavirus (HPV) circulating tumor DNA (HPV ctDNA) was proposed as a biomarker for the detection and disease monitoring of HPV-related cancers. One hundred eighty plasma samples obtained from women diagnosed with HPV16-positive cervical cancer (
Luisa Galati, Jean-Damien Combes, Florence Le Calvez-Kelm, Sandrine McKay-Chopin, Nathalie Forey, Mathis Ratel, James McKay, Tim Waterboer, Lea Schroeder, Gary Clifford, Massimo Tommasino, Tarik Gheit   +11 more
doaj   +1 more source

HPV16 variants.

, 2018
(A) The distributions of two HPV16 variant groups differ significantly in oropharyngeal and in cervical cancer. (B) Schematic phylogenetic tree for HPV16 based on Cornet et al. 2012 [30]. NA variants were considered a separate group.
Susan M. Fennewald (5703743), Vicente A. Resto (349111), John H. Lee (334901), Suimin Qiu (151100), Dianne I. Lou (194248), Bailey A. LeConte (5703740), Peter Szaniszlo (349109), Nai-Wei Chen (5703746)   +7 more
core   +1 more source

Extended High‐Risk HPV Genotyping With BD Onclarity Enhances Anal Cancer Screening Among High‐Risk Populations: A Cross‐Sectional Study

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Anal cancer rates are rising among women, immunocompromised individuals, and Men who have sex with Men (MSM), independent of HIV status. While high‐resolution anoscopy remains the diagnostic standard, limited access has increased interest in alternative screening.
Daisy Maharjan, Joshua Waters, Melissa Randolph, Benjamin Shuler, Julie Borum, Sheila Segura   +5 more
wiley   +1 more source